Buspirone NEW
Price | Get Latest Price | |
Package | 1KG | 5KG |
Min. Order: | 1KG |
Supply Ability: | 1000KG |
Update Time: | 2024-11-01 |
Product Details
Product Name: Buspirone | CAS No.: 36505-84-7 |
EC-No.: 253-072-2 | Min. Order: 1KG |
Purity: 98% | Supply Ability: 1000KG |
Release date: 2024/11/01 | |
Appearance: White powder |
Description:
Information
Brand Name: BuSpar, Vanspar
Chemical Name: Buspirone hydrochloride
Type: Anxiolytic (anti-anxiety medication)
Uses
Generalized Anxiety Disorder (GAD):
Buspirone is primarily used to treat generalized anxiety disorder, a condition characterized by excessive and uncontrollable worry about various aspects of life. It helps to reduce symptoms such as restlessness, irritability, and difficulty concentrating.
Short-term Anxiety Relief:
Buspirone can also be used for the short-term relief of anxiety symptoms. It is particularly useful for patients who need an anxiolytic without the sedative effects often associated with benzodiazepines.
Mechanism of Action
Serotonin Receptor Agonism: Buspirone works by acting as a partial agonist at the 5-HT1A receptors, which are a type of serotonin receptor in the brain. This action helps to normalize the levels of serotonin, a neurotransmitter involved in mood regulation.
Dopamine Receptor Modulation: Buspirone also has a mild effect on dopamine receptors (D2), which may contribute to its anxiolytic properties.
Precautions
Liver and Kidney Function: Buspirone is metabolized in the liver and excreted by the kidneys. Patients with liver or kidney impairment should use Buspirone with caution, and dose adjustments may be necessary.
Avoid Alcohol: Alcohol can increase the sedative effects of Buspirone and should be avoided.
Drug Interactions: Buspirone can interact with other medications, including monoamine oxidase inhibitors (MAOIs), other antidepressants, and certain antibiotics. It is important to inform your healthcare provider of all medications you are taking.
Pregnancy and Nursing: The safety of Buspirone during pregnancy and breastfeeding has not been well-established. It should be used only if the potential benefits justify the potential risks.
Side Effects
Common Side Effects:
Dizziness
Nausea
Headache
Nervousness or restlessness
Light-headedness
Dry mouth
Fatigue
Less Common but Serious Side Effects:
Serotonin syndrome (symptoms include agitation, hallucinations, rapid heart rate, and fever)
Allergic reactions (rash, itching, swelling, difficulty breathing)
Movement disorders (tremors, muscle stiffness)
Monitoring
Effectiveness: Regular follow-up with a healthcare provider is necessary to monitor the effectiveness of Buspirone and make any necessary dose adjustments.
Side Effects: Patients should be monitored for side effects, particularly any signs of serotonin syndrome or allergic reactions.
Liver and Kidney Function: Periodic liver and kidney function tests may be recommended, especially in patients with pre-existing conditions affecting these organs.
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