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Postion:Product Catalog >API>Nervous system drugs>Anxiolytics>Buspirone
Buspirone
  • Buspirone
  • Buspirone

Buspirone NEW

Price Get Latest Price
Package 1KG 5KG
Min. Order: 1KG
Supply Ability: 1000KG
Update Time: 2024-11-01

Product Details

Product Name: Buspirone CAS No.: 36505-84-7
EC-No.: 253-072-2 Min. Order: 1KG
Purity: 98% Supply Ability: 1000KG
Release date: 2024/11/01
Appearance: White powder

Description: 

Information

Brand Name: BuSpar, Vanspar

Chemical Name: Buspirone hydrochloride

Type: Anxiolytic (anti-anxiety medication)

Uses

Generalized Anxiety Disorder (GAD):

Buspirone is primarily used to treat generalized anxiety disorder, a condition characterized by excessive and uncontrollable worry about various aspects of life. It helps to reduce symptoms such as restlessness, irritability, and difficulty concentrating.

Short-term Anxiety Relief:

Buspirone can also be used for the short-term relief of anxiety symptoms. It is particularly useful for patients who need an anxiolytic without the sedative effects often associated with benzodiazepines.

Mechanism of Action

Serotonin Receptor Agonism: Buspirone works by acting as a partial agonist at the 5-HT1A receptors, which are a type of serotonin receptor in the brain. This action helps to normalize the levels of serotonin, a neurotransmitter involved in mood regulation.

Dopamine Receptor Modulation: Buspirone also has a mild effect on dopamine receptors (D2), which may contribute to its anxiolytic properties.

Precautions

Liver and Kidney Function: Buspirone is metabolized in the liver and excreted by the kidneys. Patients with liver or kidney impairment should use Buspirone with caution, and dose adjustments may be necessary.

Avoid Alcohol: Alcohol can increase the sedative effects of Buspirone and should be avoided.

Drug Interactions: Buspirone can interact with other medications, including monoamine oxidase inhibitors (MAOIs), other antidepressants, and certain antibiotics. It is important to inform your healthcare provider of all medications you are taking.

Pregnancy and Nursing: The safety of Buspirone during pregnancy and breastfeeding has not been well-established. It should be used only if the potential benefits justify the potential risks.

Side Effects

Common Side Effects:

Dizziness

Nausea

Headache

Nervousness or restlessness

Light-headedness

Dry mouth

Fatigue

Less Common but Serious Side Effects:

Serotonin syndrome (symptoms include agitation, hallucinations, rapid heart rate, and fever)

Allergic reactions (rash, itching, swelling, difficulty breathing)

Movement disorders (tremors, muscle stiffness)

Monitoring

Effectiveness: Regular follow-up with a healthcare provider is necessary to monitor the effectiveness of Buspirone and make any necessary dose adjustments.

Side Effects: Patients should be monitored for side effects, particularly any signs of serotonin syndrome or allergic reactions.

Liver and Kidney Function: Periodic liver and kidney function tests may be recommended, especially in patients with pre-existing conditions affecting these organs.


Company Profile Introduction

We are experts in providing raw materials, resources, customized manufacturing, and much more. We especially pride ourselves on the partnership in the manufacturing of high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients. Among them, our key client industrial sectors around the globe are: Pharmaceuticals. Cosmetics. Nutritional Supplements. And Special Chemicals.

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