BT-13 NEW
Price | $36 | $52 | $88 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-13 |
Product Details
Product Name: BT-13 | CAS No.: 924537-98-4 |
Purity: 99.23% | Supply Ability: 10g |
Release date: 2024/11/13 |
Product Introduction
Bioactivity
名稱 | BT-13 |
描述 | BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro. |
體外活性 | BT-13 stimulates phosphorylation of RET and RET-dependent intracellular signaling, but does not activate the BDNF receptor TrkB, the NGF receptor TrkA, or associated intracellular signaling in the absence of RET. |
體內(nèi)活性 | In rats with surgery-induced neuropathy, BT-13 (20 and 25mg/kg in rats induced by ligation of left L5 and L6 spinal nerves) has a slight antinociceptive/antihyperalgesic effect and protected DRG neurons. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 25 mg/mL (48.31 mM), Sonication is recommended. |
關(guān)鍵字 | RET | BT-13 | BT 13 | Inhibitor | inhibit | BT13 |
相關(guān)產(chǎn)品 | Cabozantinib | Fedratinib | Regorafenib monohydrate | Regorafenib Hydrochloride | SGI-7079 | Regorafenib | AST 487 | Amuvatinib | ON123300 | Lenvatinib mesylate | Lenvatinib | Selpercatinib |
相關(guān)庫 | 細(xì)胞凋亡化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | NO PAINS 化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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