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Postion:Product Catalog >BRD0639
BRD0639
  • BRD0639

BRD0639 NEW

Price $51 $122 $198
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: BRD0639 CAS No.: 2760881-74-9
Purity: 99.85% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBRD0639
DescriptionBRD0639 is a pioneering inhibitor targeting the interaction between PRMT5 and its substrate adaptor. As a competitive inhibitor of the PRMT5 binding motif (PBM), BRD0639 facilitates the investigation of activities dependent on PBM-associated PRMT5 functions [1].
In vitroBRD0639, a pioneering PBM-competitive small molecule, facilitates the research of PBM-dependent PRMT5 activities and aids in developing specific PRMT5 inhibitors. It effectively binds to the cellular target, efficiently inhibiting the interaction between full-length PRMT5 and RIOK1 proteins with IC50 values of 7.5 uM and 16 uM in permeabilized and living cells, respectively. Moreover, BRD0639 decreases SDMA levels in proteins impacted by genetic alterations of the PRMT5 binding motif (PBM) site [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/ml (126.06 mM)
KeywordsBRD0639 | BRD 0639 | BRD-0639
Inhibitors RelatedBIX-01294 trihydrochloride | Tazemetostat | Piribedil | XY1 | UNC 0631 | GSK126 | MAK683 | EZM 2302 | EPZ015666 | AMI-1 free acid | MS37452 | MRTX-1719
Related Compound LibrariesHistone Modification Compound Library | Reprogramming Compound Library | Methylation Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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