Bradykinin (2-9) NEW
| Price | $44 | $63 | $97 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-17 |
Product Details
| Product Name: Bradykinin (2-9) | CAS No.: 16875-11-9 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/17 |
Product Introduction
Bioactivity
| 名稱 | Bradykinin (2-9) |
| 描述 | Bradykinin (2-9) (Des-Arg1-bradykinin) is an amino-truncated peptide compound that is a metabolite of Bradykinin. It is formed by the cleavage action of Aminopeptidase P. |
| 體外活性 | The Bradykinin peptide system, crucial for cardiovascular and renal functions, is examined using a highly sensitive amino terminal-directed radioimmunoassay combined with high-performance liquid chromatography. This method allows for the precise measurement of various Bradykinin peptides, including Bradykinin-(1-7), Bradykinin-(1-8), and Bradykinin-(1-9). An additional carboxy terminal-directed radioimmunoassay facilitates the characterization of these peptides in rat kidney and blood. The primary findings indicate that Bradykinin-(1-9) and Bradykinin-(1-7) are the most abundant in the kidney, with significantly lower concentrations of Bradykinin-(1-8) and Bradykinin-(4-9), while Bradykinin-(2-9) and Bradykinin-(3-9) are undetectable. Blood analysis shows very low levels of Bradykinin-(1-9), with other peptides falling below detection thresholds. Administration of the ACE inhibitor Perindopril significantly increases renal levels of Bradykinin-(1-8) and Bradykinin-(1-9), altering the Bradykinin-(1-7)/Bradykinin-(1-9) ratio. This radioimmunoassay approach is also effectively applied to heart, aorta, brown adipose tissue, adrenal, lung, and brain tissues, identifying similar abundance levels of Bradykinin-(1-7) and Bradykinin-(1-9), with Bradykinin-(1-8) present in lower amounts. |
| 存儲條件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 10 mM |
| 關鍵字 | Bradykinin (29) | Bradykinin (2 9) | Bradykinin | Bradykinin Receptor | Bradykinin (2-9) | inhibit | Inhibitor |
| 相關產(chǎn)品 | Safotibant | [Des-Arg9]-Bradykinin acetate | B-Raf IN 14 | Lys-Bradykinin acetate(342-10-9 free base) | Anatibant 2HCl | (Hyp3)-Bradykinin acetate | MK-0686 | ELN-441958 | Sar-[D-Phe8]-des-Arg9-Bradykinin acetate | 5-Hydroxy-1-methylhydantoin |
| 相關庫 | 經(jīng)典已知活性庫 | 疼痛相關化合物庫 | 膜蛋白靶向化合物庫 | 多肽分子庫 | NO PAINS 化合物庫 | 已知活性化合物庫 | GPCR靶點分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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