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Postion:Product Catalog >BOS-318
BOS-318
  • BOS-318

BOS-318 NEW

Price $41 $97 $159
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: BOS-318 CAS No.: 2387633-15-8
Purity: 99.06% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱BOS-318
描述BOS-318 is a Furin inhibitor with IC50 of 1.9 nM, and has the characteristics of slow dissociation, high selectivity, and cell permeability.
體外活性METHODS: PEA and CuFi-1 cells were treated with BOS-318 (0.03, 0.1, 0.3, 1 μM, 72 hours) and PEA and cell viability was monitored to investigate the protective effect of BOS-318 against the toxic effects of bacterial toxins activated by Furin protein. RESULTS The cell viability of CuFi-1 cells treated with PEA was approximately 2% of the control level. A single 0.3 μM dose of BOS-318 significantly increased the cell viability of PEA-treated cells to approximately 88% of the control level. [1]
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 12.5 mg/mL (21.87 mM), Sonication is recommended.
關(guān)鍵字Furin | Inhibitor | ENaC | neutrophil elastase | inhibit | BOS318 | BOS 318 | BOS-318
相關(guān)庫高選擇性抑制劑庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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