Boc-Val-Ala NEW
Price | Get Latest Price | ||
Package | 1kg | 10kg | 100kg |
Min. Order: | 1kg |
Supply Ability: | 1T+ |
Update Time: | 2024-11-07 |
Product Details
Product Name: Boc-Val-Ala | CAS No.: 70396-18-8 |
Min. Order: 1kg | Purity: 98%+ |
Supply Ability: 1T+ | Release date: 2024/11/07 |
Product Name: | Boc-Val-Ala |
CAS: | 70396-18-8 |
MF: | C13H24N2O5 |
MW: | 288.34 |
Synonyms: | (S)-2-((S)-2-(tert-butoxycarbonylaMino)-3-MethylbutanaMido)propanoicacid;(Tert-Butoxy)CarbonylVal-Ala-OH;N-Boc-L-valyl-L-alanine;(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]propanoicacid;L-Alanine,N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-;(tert-Butoxycarbonyl)-L-valyl-L-alanine;Boc-Val-Ala;Boc-L-Valyl-L-Alanin |
Product Categories: | Amino Acid Derivatives;Peptide Compound |
Application: | Boc-Val-Ala is primarily used in the synthesis of Antibody-Drug Conjugates (ADCs). ADCs are a class of drugs that combine the specificity of antibodies with the cytotoxic activity of small molecule drugs. The linker, in this case Boc-Val-Ala, serves as a cleavable bridge between the antibody and the cytotoxic payload. When the ADC binds to its target antigen on the surface of a tumor cell, the linker is cleaved by intracellular enzymes, releasing the cytotoxic drug. This allows the drug to specifically target and kill tumor cells while minimizing damage to healthy cells. The application of Boc-Val-Ala in ADCs is crucial as it controls the stability of the linker, which in turn affects the release of the cytotoxic drug. The linker needs to be stable enough to maintain the integrity of the ADC until it reaches the target cell but also cleavable enough to release the drug effectively. |
Manufacturer: | Sichuan HongRi Pharma-Tech Co., Ltd. |
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- Since: 2021-03-30
- Address: A38-2, No. 66, Nanhu road, Deyang City, Sichuan Province (Jiuwei Blue Valley)