BOC-D-FMK NEW
Price | $47 | $147 | $222 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: BOC-D-FMK | CAS No.: 634911-80-1 |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | BOC-D-FMK |
Description | Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM). |
In vitro | Boc-D-fmk inhibits TNFα-stimulated reactive oxygen species (ROS) generation [1]. Boc-D-fmk (50 μM) prevents genistein-induced apoptosis of p815 cells. The release of mitochondrial apoptotic factors is inhibited by Boc-D-fmk [2]. |
In vivo | Boc-D-FMK-fmk significantly reduces apoptosis in hepatocytes of bile duct-ligated rats, potentially enhancing survival rates following endotoxin exposure [3]. A single injection of Boc-D-FMK offers prolonged protection, exceeding 8 weeks, against root avulsion-induced death in motor neurons (MNs), enabling these treated MNs to regenerate axons into an implanted peripheral nerve (PN) graft and successfully reinnervate the target muscle [4]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 125 mg/mL (474.82 mM) |
Keywords | BOCDFMK | BOC-D-FMK | Inhibitor | inhibit | Caspase | Apoptosis | BOC D FMK |
Inhibitors Related | Stavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin |
Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Protease Inhibitor Library | Pyroptosis Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Cancer Compound Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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