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Postion:Product Catalog >BOC-D-FMK
BOC-D-FMK
  • BOC-D-FMK

BOC-D-FMK NEW

Price $47 $147 $222
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: BOC-D-FMK CAS No.: 634911-80-1
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameBOC-D-FMK
DescriptionBoc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).
In vitroBoc-D-fmk inhibits TNFα-stimulated reactive oxygen species (ROS) generation [1]. Boc-D-fmk (50 μM) prevents genistein-induced apoptosis of p815 cells. The release of mitochondrial apoptotic factors is inhibited by Boc-D-fmk [2].
In vivoBoc-D-FMK-fmk significantly reduces apoptosis in hepatocytes of bile duct-ligated rats, potentially enhancing survival rates following endotoxin exposure [3]. A single injection of Boc-D-FMK offers prolonged protection, exceeding 8 weeks, against root avulsion-induced death in motor neurons (MNs), enabling these treated MNs to regenerate axons into an implanted peripheral nerve (PN) graft and successfully reinnervate the target muscle [4].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 125 mg/mL (474.82 mM)
KeywordsBOCDFMK | BOC-D-FMK | Inhibitor | inhibit | Caspase | Apoptosis | BOC D FMK
Inhibitors RelatedStavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin
Related Compound LibrariesApoptosis Compound Library | Bioactive Compound Library | Protease Inhibitor Library | Pyroptosis Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Cancer Compound Library | Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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