BIX02189 NEW

Price	$29	$46	$68
Package	2mg	5mg	10mg

Min. Order:
Supply Ability:	10g
Update Time:	2024-11-13

Product Details

Product Name: BIX02189	CAS No.: 1265916-41-3
Purity: 97.84%	Supply Ability: 10g
Release date: 2024/11/13

Product Introduction

Bioactivity

名稱	BIX02189
描述	BIX02189 is a potent and selective inhibitor of MEK5 and ERK5 (IC50: 1.5 nM and 59 nM).
體外活性	BIX02189, which inhibited catalytic function of purified, MEK5 enzyme.?The MEK5 inhibitors blocked phosphorylation of ERK5, without affecting phosphorylation of ERK1/2 in sorbitol-stimulated HeLa cells.?The compounds also inhibited transcriptional activation of MEF2C, a downstream substrate of the MEK5/ERK5 signaling cascade, in a cellular trans-reporter assay system[1].
存儲(chǔ)條件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
溶解度	DMSO : 49.4 mg/mL (112.14 mM)
關(guān)鍵字	Mitogen-activated protein kinase kinase \| inhibit \| MAP2K \| BIX02189 \| MAPKK \| MEK \| BIX-02189 \| Extracellular signal regulated kinases \| Inhibitor \| ERK
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.