Product Details
Product Name:
BI8626 |
CAS No.:
1875036-75-1 |
Supply Ability:
10g |
Release date:
2024/11/18 |
Product Introduction
Bioactivity
名稱(chēng) | BI8626 |
描述 | BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZAP-70, CD25, and other activation markers, and inhibits the proliferation of CD4 T-cells. |
體外活性 | In LS174T cells, BI8626 (0μM, 5μM, 10μM, 15μM, 20μM; 0-4 days) delayed progression through all phases of the cell cycle, with the most pronounced effect on the G1 phase[1]. |
存儲(chǔ)條件 | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 60 mg/mL (136.20 mM), Sonication is recommended.
|
關(guān)鍵字 | BI-8626 | BI8626 | BI 8626 |
相關(guān)產(chǎn)品 | NSC697923 | PYZD-4409 | Nutlin-3 | NAcM-OPT | RG7112 | PYR-41 | NSC232003 | NAE-IN-M22 | Indole-3-carbinol | Idasanutlin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$84.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-18 |