BI-2493 NEW
Price | $630 | $1550 | $2480 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: BI-2493 | CAS No.: 2937344-16-4 |
Purity: 99.49% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | BI-2493 |
Description | BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865. |
In vitro | METHODS: ASPC1, HPAC and H727 cells were treated with BI-2493 (Log (1-4nM)), and cell viability was detected after 72 hours. RESULTS BI-2493 inhibited the growth of ASPC1, HPAC and H727 cells. [1] |
In vivo | METHODS: A cell line-derived xenograft model was established, and mice were randomly assigned according to tumor size (n = 7-8 mice per treatment group) and treated with BI-2493 (10-90 mg/kg, orally twice daily) . RESULTS BI-2493 attenuated tumor growth in xenograft model mice. [1] |
Storage | Shipping with blue ice. |
Solubility Information | DMSO : 60 mg/mL (129.99 mM), Sonication and heating are recommended. |
Keywords | BI2493 | BI 2493 | BI-2493 |
Inhibitors Related | Adagrasib | (S)-AMG-510 | CCG-257081 | Ketoconazole | Deltarasin | ZCL278 | MRTX1133 | Salirasib | RMC-6236 | (S)-(-)-Perillyl alcohol | CASIN | Sotorasib |
Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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