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Postion:Product Catalog >BAY 2666605
BAY 2666605
  • BAY 2666605

BAY 2666605 NEW

Price $59 $148 $238
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: BAY 2666605 CAS No.: 2275774-60-0
Purity: 99.98% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱BAY 2666605
描述BAY 2666605 is an orally active inhibitor of PDE3A (IC50 = 87 nM) and PDE3B (IC50 = 50 nM) with noted anticancer effects.
體外活性BAY 2666605 inhibits brain cancer(glioma, more specifically glioblastoma, astrocytoma), breast cancer (ductal carcinoma and adenocarcinoma), cervical cancer, AML(erythroleukemia), lung cancer(NSCLC adenocarcinoma and SCLC), skin cancer(melanoma), esophagus cancer (squamous cell carcinoma), ovarian cancer, (teratocarcinoma, adenocarcinoma), pancreas cancer and prostatic cancer[1].
體內(nèi)活性In murine xenotransplantation models of human cancer, BAY 2666605 (5 mg/kg; p.o) exhibits anti-tumor efficacy[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 245 mg/mL (695.47 mM), Sonication is recommended.
關(guān)鍵字Phosphodiesterase (PDE) | PDE3A-SLFN12 Complex | orally active | Inhibitor | inhibit | BAY-2666605 | BAY2666605 | BAY 2666605 | anticancer effect
相關(guān)產(chǎn)品Theophylline monohydrate | Diphylline | Acefylline | Roflumilast | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Vardenafil hydrochloride | Doxofylline
相關(guān)庫經(jīng)典已知活性庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗心血管疾病化合物庫 | 口服活性化合物庫 | 免疫/炎癥分子化合物庫 | 已知活性化合物庫 | 含氟化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫 | 抗癌藥物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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