Azacitidine NEW
Price | Get Latest Price |
Package | 1g |
Min. Order: | 1g |
Supply Ability: | 100kg |
Update Time: | 2024-11-19 |
Product Details
Product Name: Azacitidine | CAS No.: 320-67-2 |
Min. Order: 1g | Purity: 98% HPLC |
Supply Ability: 100kg | Release date: 2024/11/19 |
Azacitidine is a cytidine nucleoside analog that produces antitumor effects by causing DNA demethylation and direct cytotoxicity to abnormal hematopoietic cells in the bone marrow. The concentration at which azacitidine has the maximum inhibitory effect on DNA methylation in vitro has no obvious inhibitory effect on DNA synthesis. Demethylation of DNA restores the normal function of genes, which is critical for cell differentiation and proliferation. The cytotoxic effects of azacitidine cause the death of rapidly dividing cells, including cancer cells that do not respond to normal growth regulatory mechanisms. Cells in the non-proliferative phase are relatively insensitive to azacitidine. It can be used to treat intermediate-2/high-risk myelodysplastic syndrome, acute myeloid leukemia (AML) with 20-30% bone marrow blasts, and chronic myelomonocytic leukemia (CMML). It also has certain curative effect on breast cancer, intestinal cancer and melanoma.
This drug reduces the growth of cancer cells and suppresses the immune system. It is used to treat myeloid dyspoietic syndrome and certain types of leukemia.
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- Since: 2014-09-09
- Address: No.28 Hua Long Road,Ji Nan City,China
+86-13153181156
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