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Postion:Product Catalog >Apelin-12 acetate
Apelin-12 acetate
  • Apelin-12 acetate

Apelin-12 acetate NEW

Price $228 $320 $497
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Apelin-12 acetate Purity: 98.82%
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameApelin-12 acetate
DescriptionApelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons.
In vivoApelin-12 acetate significantly improves the neurobehavioral score of the mice with ischemia-reperfusion injury and alleviates brain edema and damage to neurons. Apelin-12 acetate inhibits the morphological changes and apoptosis of neuronal cells in the ischemic penumbra of mice. Apelin-12 acetate downregulates the expression of Bax and caspase-3, inhibits the activity of caspase-3, and upregulates the expression of Bcl-2, an anti-apoptotic protein[2].
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 22.5 mg/mL (15.17 mM)
KeywordsApelin-12 Acetate | 229961-08-4 | 229961-08-4 Free base
Inhibitors RelatedAstragaloside IV | SB 202190 | Anisomycin
Related Compound LibrariesAnti-Colorectal Cancer Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Peptide Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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