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Postion:Product Catalog >Anti-inflammatory agent 51
Anti-inflammatory agent 51
  • Anti-inflammatory agent 51

Anti-inflammatory agent 51 NEW

Price $52 $87 $143
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Anti-inflammatory agent 51 CAS No.: 2911610-03-0
Purity: 99.46% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAnti-inflammatory agent 51
DescriptionAnti-inflammatory agent 51 is an amide/sulfonamide derivative with anti-inflammatory and potentially anti-tumor activity and inhibition of NF-κB activation, which can be used to study acute lung injury and ulcerative colitis.
In vitroAnti-inflammatory agent 51 (compound 11d) effectively reduces the release of IL-6 (IC50 value of 0.61 μM) and TNF-α (IC50 of 4.34 μM), decreases cytokine mRNA levels in J774A.1 cells, restores IκBα, and inhibits the nuclear translocation of phosphorylated p65 [1].
In vivoAnti-inflammatory agent 51 (compound 11d) mitigates lipopolysaccharide (LPS)-induced acute lung injury (ALI) and ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice [1].
Storagestore at low temperature | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/mL (120.36 mM), Sonication is recommended.
KeywordsAntiinflammatoryagent51
Inhibitors RelatedSodium Houttuyfonate | Lidocaine | Diethylmaleate | Glucosamine | sodium lauroyl-α-hydroxyethyl sulfonate | Lidocaine hydrochloride | 5-Aminosalicylic Acid | Indole-3-carbinol | Diallyl disulfide | Sodium salicylate
Related Compound LibrariesBioactive Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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