Anti-inflammatory agent 51 NEW
Price | $52 | $87 | $143 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Anti-inflammatory agent 51 | CAS No.: 2911610-03-0 |
Purity: 99.46% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Anti-inflammatory agent 51 |
Description | Anti-inflammatory agent 51 is an amide/sulfonamide derivative with anti-inflammatory and potentially anti-tumor activity and inhibition of NF-κB activation, which can be used to study acute lung injury and ulcerative colitis. |
In vitro | Anti-inflammatory agent 51 (compound 11d) effectively reduces the release of IL-6 (IC50 value of 0.61 μM) and TNF-α (IC50 of 4.34 μM), decreases cytokine mRNA levels in J774A.1 cells, restores IκBα, and inhibits the nuclear translocation of phosphorylated p65 [1]. |
In vivo | Anti-inflammatory agent 51 (compound 11d) mitigates lipopolysaccharide (LPS)-induced acute lung injury (ALI) and ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice [1]. |
Storage | store at low temperature | Shipping with blue ice. |
Solubility Information | DMSO : 60 mg/mL (120.36 mM), Sonication is recommended. |
Keywords | Antiinflammatoryagent51 |
Inhibitors Related | Sodium Houttuyfonate | Lidocaine | Diethylmaleate | Glucosamine | sodium lauroyl-α-hydroxyethyl sulfonate | Lidocaine hydrochloride | 5-Aminosalicylic Acid | Indole-3-carbinol | Diallyl disulfide | Sodium salicylate |
Related Compound Libraries | Bioactive Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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