AMPK-IN-3 NEW
| Price | $109 | $263 | $422 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: AMPK-IN-3 | CAS No.: 2417674-27-0 |
| Purity: 99.13% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | AMPK-IN-3 |
| 描述 | AMPK-IN-3 is a novel, selective and potent AMPK inhibitor with inhibitory effects on AMPK (α2), AMPK (α1) and KDR, with IC50 values of 60.7, 107 and 3820 nM, respectively.AMPK-IN-3 showed anticancer activity in K562 cells. |
| 體外活性 | At a concentration of 100 nM, AMPK-IN-3 exhibits inhibition values of 64%, 43%, 41%, and 29% for AMPK(α2), FLT1, JAK1 JH2-pseudokinase, and AMPK(α1), respectively[1].In K562 cells, AMPK-IN-3, when applied at concentrations of 0.195313, 0.78125, 3.125, 12.5, and 50 μM for 2 hours, reduces the level of p-ACC[1]. For a duration of 24, 48, and 72 hours, AMPK-IN-3, within the concentration range of 1-100 μM, demonstrates potent inhibition of cellular AMPK activity without affecting cell viability[1]. |
| 存儲條件 | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (110.73 mM), Sonication is recommended. |
| 相關(guān)產(chǎn)品 | Sorafenib | Metformin hydrochloride | Chitosan oligosaccharide |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 表觀遺傳庫 | 激酶抑制劑庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1820.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-23 | |
| $2500.00/100mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-23 | |
| $1.00/1KG |
VIP7Y
|
.GZ HONESTCHEM CO.,LTD
|
2018-09-12 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY