Aminoguanidine hydrochloride NEW
| Price | $36 | $50 | $75 |
| Package | 50mg | 100mg | 200mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-09 |
Product Details
| Product Name: Aminoguanidine hydrochloride | CAS No.: 1937-19-5 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/09 |
Product Introduction
Bioactivity
| 名稱 | Aminoguanidine hydrochloride |
| 描述 | Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy. |
| 體內(nèi)活性 | Aminoguanidine ameliorates neonatal hypoxic-ischemic brain damage and that temporal profiles of NO correlated with the neuroprotective effect of aminoguanidine. Neuroprotection by AG is attributable to suppression of NO produced by iNOS after the end of the hypoxic period, during the reoxygenation phase. The half-life of AG is estimated to be between 6 and 8 h in vivo and approximately 4.4 h in human with normal renal function.AG is also an inhibitor of the formation of advanced glycation end products. Systematically administered advanced glycation end product–modified BSA increases cerebral infarct size in an adult rat, which is attenuated by AG[2]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (452.28 mM) Ethanol : < 1 mg/mL (insoluble or slightly soluble) H2O : 20 mg/mL (180.9 mM) |
| 關(guān)鍵字 | Aminoguanidine Hydrochloride | Nitric oxide synthases | GER 11 | GER-11 | NOS | Aminoguanidine hydrochloride | Aminoguanidinium | CP-12009-18 Tartrate | NO Synthase | inhibit | GER11 | Inhibitor | Pimagedine Hydrochloride | Aminoguanidine |
| 相關(guān)產(chǎn)品 | L-NAME hydrochloride | Mifepristone | Dexamethasone acetate | S-Methylisothiourea sulfate | L-Arginine | Ethyl cinnamate | Methylene Blue trihydrate | Diallyl disulfide | L-Arginine hydrochloride |
| 相關(guān)庫 | 非甾體類抗炎化合物庫 | 經(jīng)典已知活性庫 | 抗糖尿病庫 | 藥物功能重定位化合物庫 | 神經(jīng)保護(hù)化合物庫 | 抑制劑庫 | NO PAINS 化合物庫 | FDA 上市藥物庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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