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Postion:Product Catalog >ALZ-801
ALZ-801
  • ALZ-801

ALZ-801 NEW

Price $38 $54 $89
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-13

Product Details

Product Name: ALZ-801 CAS No.: 1034190-08-3
Purity: 99.36% Supply Ability: 10g
Release date: 2024/11/13

Product Introduction

Bioactivity

名稱ALZ-801
描述ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, a valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound.
體內活性The ALZ-801: Tramiprosate ratio in plasma and brain is 1.8 and 3.1, respectively in male CD-1 mice[1]. ALZ-801 (oral administration; 172?mg/kg; single dose) shows average AUCt values of 58,758 and 5841 ng/ml.h in plasma and brain, respectively.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : < 1 mg/mL (insoluble or slightly soluble)
H2O : 20 mg/ml (83.93 mM), Sonication is recommended.
關鍵字β-amyloid peptide | Alzheimer | Amyloid-β | Tramiprosate | disease | inhibit | ALZ-801 | Abeta | ALZ801 | β-amyloid | Inhibitor | ALZ 801
相關產品Anle138b | BSBM7 | Notoginsenoside R1 | Geniposide | Deferoxamine Mesylate | Tramiprosate | PQM130 | Dihydroergocristine mesylate | Rutin | Ginsenoside Rg2 | Methyl tridecanoate | Ginsenoside Re
相關庫神經退行性疾病化合物庫 | 經典已知活性庫 | 抗阿爾茨海默癥化合物庫 | 神經信號分子庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | NO PAINS 化合物庫 | 口服活性化合物庫 | 臨床期小分子藥物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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