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Postion:Product Catalog >Biochemical Engineering>Saccharides>Monosaccharide>AICAR
AICAR
  • AICAR

AICAR

Price $6.5
Package 50mg
Min. Order: 50mg
Supply Ability: 20kg
Update Time: 2023-04-13

Product Details

Product Name: AICAR CAS No.: 2627-69-2
EC-No.: 220-097-5 Min. Order: 50mg
Purity: 99% HPLC Supply Ability: 20kg
Release date: 2023/04/13

Acadesine is the prototype of a new class of compounds termed adenosine regulating agents. Acadesine is a purine nucleosid analogue that enters the myocyte and is immediately phosphorylated to ZMP (AICA ribotide), which is further metabolised to Inosine mono-phosphate (an intermediate in the synthesis ofadenosine triphosphate (ATP) and guanosine triphos-phate).
Claims that acadesine may serve as a substrate for ATP synthesis and result in repletion of myocardial ATP were supported by some studies and refuted by others. Because acadesine may be a precursor in the synthesis of myocardial ATP it was proposed as a possible agent of myocardial protection during ischaemia, particularly because myocardial ATP depletion has been linked to cell death.

AICAR (2627-69-2) activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal muscle autophagy via activation of FoxO3a.2 Controls smooth muscle cell hyperproliferation in vascular disease.3 ?Induces osteogenic differentiation in mesenchymal stem cells.4 Inhibits proinflammatory response in glial cells.5 Cell permeable.


Company Profile Introduction

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  • Since: 2022-07-15
  • Address: No. 1903, Building 3, Dahan HP Industrial Park, No. 1318 Huanghe North Road, Tianyuan District, Zhuz
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