Acarbose NEW
| Price | $50 |
| Package | 200mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Acarbose | CAS No.: 56180-94-0 |
| Purity: 99.88% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Acarbose |
| Description | Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity. |
| Cell Research | Cell viability is determined using the MTT assay. Cells are seeded in 24-well culture plates at a density of 2×104 cells/well, incubated for 48 h, treated with acarbose at varying concentrations (0.5, 1.0, 2.0, 3.0, and 5.0 μM) for 24 h; or pre-treated with TNF-α (20 ng/mL) for either 24 h or 48 h to evaluate the dose-dependent effects of acarbose on VSMC growth and viability, cultured with 0.5 mg/mL MTT at 37°C in a humidified atmosphere of 5% CO2 for another 4 h, and solubilized with isopropanol. The viable cell number varies directly with the concentration of formazan product measured spectrophotometrically at 563 nm. |
| In vitro | Acarbose binds to and inhibits α-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. In addition, acarbose inhibits pancreatic α-amylase which hydrolyzes complex starches to oligosaccharides in the small intestines. |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (77.45 mM) H2O : 64.5 mg/mL (100 mM) |
| Keywords | mellitus | oral | antihyperglycemic | insulin | Glucosidase | anti-diabetes | BAY g5421 | Inhibitor | BAY g-5421 | inhibit | Acarbose |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Kinase Inhibitor Library | Saccharide and Glycoside Natural Product Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | FDA-Approved Kinase Inhibitor Library | FDA-Approved Drug Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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