Acalabrutinib NEW
Price | Get Latest Price |
Package | 1g |
Min. Order: | 1g |
Supply Ability: | 1kg |
Update Time: | 2024-11-19 |
Product Details
Product Name: Acalabrutinib | CAS No.: 1420477-60-6 |
Min. Order: 1g | Purity: 98% HPLC |
Supply Ability: 1kg | Release date: 2024/11/19 |
Acotinib, also known as ACP-196, is an orally available Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. After administration, ACP-196 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents B cell activation and BTK-mediated activation of downstream survival pathways. This results in inhibition of the growth of malignant B cells overexpressing BTK. BTK, a member of the src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays important roles in B-lymphocyte development, activation, signaling, proliferation and survival.
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