Ac-DEVD-CHO acetate NEW
Price | $70 | $223 | $336 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Ac-DEVD-CHO acetate | Purity: 98.54% |
Supply Ability: 10g | Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱(chēng) | Ac-DEVD-CHO acetate |
描述 | Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3. |
體外活性 | Pretreatment with the caspase-3 inhibitor Ac-DEVD-CHO or antioxidant NAC blocked SLNT-induced apoptosis[1]. The apoptosis of SP2/0 cells was blocked by a pan-caspase inhibitor Z-VAD-FMK and caspase-3 inhibitor Ac-DEVD-CHO[2]. |
體內(nèi)活性 | Compared with model group, in CI group, the concentrations of serum BUN were decreased significantly at all time points after operation and those of Cr were decreased significantly at 6 hours, then restored to those of the sham group at 12 hours and 24 hours; the concentrations of serum TNF-α, IL-6 were decreased and those of IL-10 elevated significantly at all time points[3]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 40 mg/mL (79.61 mM) |
關(guān)鍵字 | 169332-60-9 free base | Ac-DEVD-CHO Acetate | Caspase 3 Inhibitor I | 169332-60-9 | Caspase3 Inhibitor I |
相關(guān)產(chǎn)品 | Taurochenodeoxycholic Acid | Tauroursodeoxycholate |
相關(guān)庫(kù) | 細(xì)胞凋亡化合物庫(kù) | 神經(jīng)退行性疾病化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 蛋白酶抑制劑庫(kù) | 抑制劑庫(kù) | 已知活性化合物庫(kù) | 抗癌化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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