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Postion:Product Catalog >A-3 hydrochloride
A-3 hydrochloride
  • A-3 hydrochloride

A-3 hydrochloride NEW

Price $30 $61 $97
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: A-3 hydrochloride CAS No.: 78957-85-4
Purity: 99.32% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameA-3 hydrochloride
DescriptionA-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1], and also inhibits PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM), and myosin light chain kinase (MLCK) (Ki=7.4 μM).
In vitroA-3 hydrochloride competitively inhibits MLC-kinase with respect to ATP, with a Ki value of 7.4 μM. It also competitively inhibits cAMP-dependent protein kinase, cGMP-dependent protein kinase, protein kinase C, casein kinase I, and casein kinase II with ATP, exhibiting Ki values of 4.3 μM, 3.8 μM, 47 μM, 80 μM, and 5.1 μM, respectively[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 125 mg/mL (389.14 mM), Sonication is recommended.
KeywordsCalmodulin-dependent kinases | CaMK | inhibit | Casein Kinase | PKC | inhibitor | PKA | A 3 hydrochloride | cAMP | calmodulin | A3 Hydrochloride | kinase | A-3 | MLC-kinase | Calmodulin-dependent protein kinases | Protein kinase C | Protein kinase A | A 3 Hydrochloride | A 3 | A-3 Hydrochloride | casein | A3 hydrochloride
Inhibitors RelatedDarovasertib | α-Vitamin E | Acefylline | Staurosporine | Emodin | Melatonin | CaMKP Inhibitor | Mitoxantrone dihydrochloride | JAK1/2/3 Inhibitor 1
Related Compound LibrariesReprogramming Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | TGF-beta/Smad Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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