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Postion:Product Catalog >Biochemical Engineering>Inhibitors>TGF-beta / Smad>PKC inhibitor>GO 6976
GO 6976
  • GO 6976
  • GO 6976
  • GO 6976

GO 6976

Price $1
Package 1g
Min. Order: 1g
Supply Ability: 200kg
Update Time: 2020-01-13

Product Details

Product Name: GO 6976 CAS No.: 136194-77-9
Min. Order: 1g Purity: 99%
Supply Ability: 200kg Release date: 2020/01/13

Mary

 

Product Name:
GO 6976
Synonyms:
InSolution G 6976 - CAS 136194-77-9 - Calbiochem;5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;Go6976,5,6,7,13-Tetrahydro-13-Methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile;PD406976;InSolution? G? 6976;12-(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO(2,3-A)PYRROLO(3,4-C)-CARBAZOLE;12-2(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE;GO 6976
CAS:
136194-77-9
MF:
C24H18N4O
MW:
378.43
EINECS:
 
Product Categories:
-;Inhibitor;Inhibitors
Mol File:
136194-77-9.mol
Article illustration
 
GO 6976 Chemical Properties
Boiling point 
652.3±55.0 °C(Predicted)
density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
Off-white solid
pka
14.39±0.20(Predicted)
 
Safety Information
Safety Statements 
22-24/25
MSDS Information
 
 
GO 6976 Usage And Synthesis
Biological Activity
Potent protein kinase C (PKC) inhibitor (IC 50 = 7.9 nM). In vitro, discriminates between Ca 2+ -dependent and -independent isoforms of PKC; selectively inhibits PKC α and PKC β 1 (IC 50 values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKC δ , - ε , or - ζ (IC 50 > 3 μ M). Also inhibits TrkA, TrkB, JAK2 and JAK3 tyrosine kinases (IC 50 values are 5, 30, 130 and 370 nM respectively).
 
GO 6976 Preparation Products And Raw materials
 
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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