8-Hydroxyquinoline
Price | $1 |
Package | 25kg |
Min. Order: | 1kg |
Supply Ability: | 20MT |
Update Time: | 2022-08-27 |
Product Details
Product Name: 8-Hydroxyquinoline | CAS No.: 148-24-3 |
EC-No.: 205-711-1 | Min. Order: 1kg |
Purity: 99.5% | Supply Ability: 20MT |
Release date: 2022/08/27 |
8-Hydroxyquinoline cas148-24-3 Preservatives, disinfectants and insecticides, used as transcription inhibitors
8-Hydroxyquinoline Identification
Synonyms 8-Quinolinol; Quinolin-8-ol; Oxine
Molecular Formula C9H7NO
Molecular Weight 145.16
CAS Number 148-24-3
EINECS/ELINCS 205-711-1
Properties
Appearance White or light yellow crystalline powder
Boiling point 267oC (752mmHg)
Solubility Insoluble in water, soluble in ethanol and chloroform.
Stability Stable under ordinary conditions
8-Hydroxyquinoline description
8-Hydroxyquinoline has a wide variety of uses. Primarily because of their metal chelating properties, 8-hydroxyquinoline and its salts, halogenated derivatives, and metal complexes have been used as analytical reagents (Hollingshead, 1954) and as antimicrobial agents in medicine, fungicides, and insecticides (Harvey, 1975). It is also used as a preservative in cosmetics and tobacco, a chemical intermediate in dye synthesis (IARC, 1977), and a precipitating reagent for uranium and other radioactive metals in nuclear power plant liquid waste effluent. It is used in nuclear medicine with indium-111
8-Hydroxyquinoline Certificate of Analysis
Items | Standards |
Characteristics | White to the pale yellow powder |
Assay(C12H12O18P2Mg3) | ≥98.5% |
Loss on drying | ≤20% |
Heavy Metals(Pb) | ≤0.001% |
Arsenic | ≤0.0002% |
PH Value(3% aqueous solution) | 7.0-8.5 |
Color of solution | ≤70 |
Free ascorbic acid | ≤0.5% |
Free phosphoc acid | ≤1% |
Chloride | ≤0.35% |
Total aerobic count | ≤1000 per gram |
8-Hydroxyquinoline Application
8-Hydroxyquinoline is used as an intermediate for pharmaceuticals and agrochemicals. It is alos as a precipitating agent or chelating agent to separate metals. It is used in formulating anti-dandruff agents for shampoo.
8-Hydroxyqui oline is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
In aqueous solution 8-hydroxyquin oline has a pKa value of ca. It reacts with metal ions, losing the proton and forming 8-hydroxyquinolinato-chelate complexes.
The aluminium complex is a common component of organic light-emitting diodes (OLEDs). Variations in the substituents on the quino line rings affect its luminescence properties.
In the photochemically induced excited-state zwitterionic isomers are formed in which the hydrogen atom is transferred from oxygen to nitrogen.
The complexes as well as the heterocycle itself exhibit antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor. Its solution in alcohol is used in liquid bandages. It once was of interest as an anti-cancer drug.
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- Since: 2020-08-28
- Address: 358# Hannan Road, Shamao Street, Hanan,Wuhan,Hubei China