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Postion:Product Catalog >API>Antibiotics>Cephalosporins Drugs>Unii-p9vxv1408y
Unii-p9vxv1408y
  • Unii-p9vxv1408y
  • Unii-p9vxv1408y
  • Unii-p9vxv1408y
  • Unii-p9vxv1408y
  • Unii-p9vxv1408y

Unii-p9vxv1408y

Price $7
Package 1KG
Min. Order: 1KG
Supply Ability: 100KG
Update Time: 2020-01-01

Product Details

Product Name: Unii-p9vxv1408y CAS No.: 866021-48-9
Min. Order: 1KG Purity: 99%
Supply Ability: 100KG Release date: 2020/01/01
Name : Judy

JD 607  Judy Liang    Judy@coreychem.com 

Product Name: Unii-p9vxv1408y
Synonyms: 4-[2-[[(6R;4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methylpyridinium acetate hydrate;Ceftaroline Impurity8;7R)-2-Carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1;Ceftaroline;Unii-p9vxv1408y;acetic acid,(6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate,hydrate;Ceftaroline Fosamil Acetate Hydrate
CAS: 866021-48-9
MF:
MW: 0
EINECS:
Product Categories: Amines;API;-;Chiral Reagents;Heterocycles
Mol File: Mol File
Unii-p9vxv1408y Structure
Unii-p9vxv1408y Chemical Properties
Safety Information
MSDS Information
Unii-p9vxv1408y Usage And Synthesis
Antimicrobial activity A semisynthetic cephalosporin formulated as the water-soluble fosamil acetate prodrug for intravenous administration. Its properties are similar to those of ceftobiprole, with which it shares an enhanced affinity for penicillin-binding protein 2′ (2a) of methicillin-resistant Staph. aureus. It is hydrolyzed by extended-spectrum β-lactamases and is not active against Amp-C derepressed strains of Gram-negative bacilli.
Pharmacokinetics Cmax 600 mg intravenous (1-h infusion): 19 mg/L end infusion
Plasma half-life: 2.6 h
Volume of distribution: 0.37 L/kg
Plasma protein binding :<20%
Like ceftobiprole, ceftaroline fosamil is rapidly hydrolyzed in plasma after intravenous infusion and excreted principally in urine. In preliminary clinical studies it appears to be well tolerated.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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