PLECONARIL

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Package	1KG

Min. Order:	1KG
Supply Ability:	kg/T
Update Time:	2019-12-20

Product Details

Product Name: PLECONARIL	CAS No.: 153168-05-9
Min. Order: 1KG	Purity: 99%
Supply Ability: kg/T	Release date: 2019/12/20

Heidi226

Email: heidi@coreychem.com

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PLECONARIL Basic information

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Product Name:

PLECONARIL

Synonyms:

Pleconaril-d4;PLECONARIL;WIN 63843;3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole;Picovir;3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-;1,2,4-Oxadiazole,3-[3,5-diMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-;VP 63843

CAS:

153168-05-9

MF:

C18H18F3N3O3

MW:

381.352

EINECS:

Product Categories:

Anti-virals;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals

Mol File:

153168-05-9.mol

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PLECONARIL Chemical Properties

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Melting point

61-62°

Boiling point

481.2±55.0 °C(Predicted)

density

1.271

storage temp.

room temp

solubility

DMSO: ≥10mg/mL (warmed)

pka

-1.33±0.10(Predicted)

form

powder

color

white to beige

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Safety Information

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Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

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MSDS Information

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PLECONARIL Usage And Synthesis

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Chemical Properties

Off-White Solid

Uses

Picornavirus replication inhibitor. Antiviral.

Pharmaceutical Applications

An oxadiazole active against most enteroviruses and rhinoviruses. It binds to the hydrophobic pocket of the virus capsid protein VP1, inducing conformational changes that lead to altered receptor binding and viral uncoating. Concerns over safety and efficacy have constrained development of the drug.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;