Eprinomectin
Price | $1 |
Package | 25Kg/Drum |
Min. Order: | 25Kg/Drum |
Supply Ability: | 1ton |
Update Time: | 2019-10-29 |
Product Details
Product Name: Eprinomectin | CAS No.: 123997-26-2 |
Min. Order: 25Kg/Drum | Purity: 99% |
Supply Ability: 1ton | Release date: 2019/10/29 |
Veterinary Drug 98% Eprinomectin Powder
Introduction
Other name: (4''R)-4''-(ACETYLAMINO)-4''-DEOXY-AVERMECTIN B1
Chemical Formula: C50H75NO14
CAS Number: 123997-26-2
EINECS NO.: 200-835-2
MW: 914.13
Melting point: 163-166ºC
Density:1.23g/cm3
Appearance: White crystalline powder
Eprinomectin is a mixture of eprinomectins B1a and B1b in a 9:1 ratio, produced from a mixture of avermectin B1a and B1b. Eprinomectin is used commercially as a topical endectocide (insecticide, miticide and nematocide) for cattle, including lactating dairy cows. Like all avermectins and milbemycins, eprinomectin acts by binding to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite, mite or insect.
It is not only a broad spectrum and the most efficacious pesticide of Avermectin kind, but also one of the lowest distribution coefficient of this kind in milk. Trials show that the product with the concentration of 0.1mg/kg or 0.05mg/kg can efficaciously prevent seven kinds of nematodes parasitic on large intestine, small intestine and stomach of cattle and sheep, the efficacy is shown as at least 97%. When it is used to cow in milk, concentration ratio in milk to in plasma is not more than 0.2. It has the advantage over other drugs against nematodes parasitic on cow during milking.
Function
It is not only a broad spectrum and the most efficacious pesticide of Avermectin kind, but also one of the lowest distribution coefficient of this kind in milk. Trials show that the product with the concentration of 0.1mg/kg or 0.05mg/kg can efficaciously prevent seven kinds of nematodes parasitic on large intestine, small intestine and stomach of cattle and sheep, the efficacy is shown as at least 97%. When it is used to cow in milk, concentration ratio in milk to in plasma is not more than 0.2. It has the advantage over other drugs against nematodes parasitic on cow during milking.
Application
Eprinomectin is moderately used in ruminants, mainly in pour-ons and injectables. So far it is not used in swine, poultry or horses. Use in cats as a spot-on (in combination with other actives) is still rather scarce. So far it is not used in dogs.
In most finished products, efficacy and safety depend not only on the amount of active ingredient(s) but also on their formulations (i.e. the type and amount of so-called inert ingredients), particularly in injectables and in topical pour-ons and spot-ons. These inert ingredients can significantly affect the pharmacokinetic behavior (e.g. absorption through the skin or from the injection site, distribution within the body, spreading throughout the body surface, etc.). Generic products usually contain the same amount of active ingredient(s) as the original product, but often in quite different formulations. In many cases, the curative (therapeutic) efficacy of the different formulations is quite comparable, but the protective (prophylactic) efficacy that determines the length of protection against re-infestations may be rather different.
Specification
Tests
Specifications
Test results
Description
White or pale yellow crystalline
powder
Complies
Ingredient
B1
B1a
≥90.0%
≥90.0%
96.02%
92.92%
Moisture
≤1.0%
0.5%
Non-dissolve in acetone
≤0.1%
0.02%
Loss on drying
≤4.0%
1.8%
Avermectin
≤0.5%
0.2%
Residue on ignition
≤0.1%
0.01%
Heavy metals
≤20ppm
Complies
Arsenic salt
≤2ppm
Complies
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- Since: 2012-02-03
- Address: No. 7, No. 7, No. 1, No. 160, Qiaokou Road, Qiaokou District, Qiaokou city.