Nimorazole
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 2kg |
| Update Time: | 2019-09-06 |
Product Details
| Product Name: Nimorazole | CAS No.: 6506-37-2 |
| Min. Order: 1KG | Purity: 95% |
| Supply Ability: 2kg | Release date: 2019/09/06 |
Abby015
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Nimorazole Basic information
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Product Name:
Nimorazole
Synonyms:
4-[2-(5-Nitroimidazol-1-yl)ethyl]morpholine;4-[2-(5-Nitro-1H-imidazol-1-yl)ethyl]morpholine;K-1900;Naxogin;Nitrimidazine;Nulogyl;1-(2-N-Morpholinylethyl)-5-nitroimidazole;Acterol
CAS:
6506-37-2
MF:
C9H14N4O3
MW:
226.23
EINECS:
229-394-4
Product Categories:
-;API;Inhibitors
Mol File:
6506-37-2.mol
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Nimorazole Chemical Properties
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Melting point
110-111°
Boiling point
367.84°C (rough estimate)
density
1.2673 (rough estimate)
refractive index
1.6300 (estimate)
NIST Chemistry Reference
Nimorazole(6506-37-2)
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Safety Information
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Toxicity
LD50 orally in mice: 1530 mg/kg (Cavalleri)
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MSDS Information
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Nimorazole Usage And Synthesis
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Uses
Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa.
Pharmaceutical Applications
An orally administered 5-nitroimidazole. It is slightly soluble in water at room temperature, soluble in alcohols, acetone and chloroform. The spectrum includes T. vaginalis, G. lamblia, E. histolytica, anaerobic bacteria and G. vaginalis. Activity against B. fragilis and Fusobacterium spp. is similar to or slightly less than that of metronidazole (mean MIC 0.25–1 mg/L).
A peak blood concentration of about 32 mg/L occurs within 2 h of a 500 mg oral dose. High concentrations are achieved in saliva and vaginal secretions. Excretion is principally via the urine where the drug appears as metabolites which display antimicrobial and antiprotozoal activity less than that of the parent drug.
It is generally well tolerated even at the high doses required in conjunction with radiotherapy for the treatment of head and neck tumors. Adverse effects are the same as those of metronidazole. Disulfiram-like reactions appear to be rare.
Clinical uses are similar to those of metronidazole. It is also used as a hypoxic radiosensitizer in the radiotherapy of head and neck tumors.
A peak blood concentration of about 32 mg/L occurs within 2 h of a 500 mg oral dose. High concentrations are achieved in saliva and vaginal secretions. Excretion is principally via the urine where the drug appears as metabolites which display antimicrobial and antiprotozoal activity less than that of the parent drug.
It is generally well tolerated even at the high doses required in conjunction with radiotherapy for the treatment of head and neck tumors. Adverse effects are the same as those of metronidazole. Disulfiram-like reactions appear to be rare.
Clinical uses are similar to those of metronidazole. It is also used as a hypoxic radiosensitizer in the radiotherapy of head and neck tumors.
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Nimorazole Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com