Butoconazole
| Price | $1 | $2 |
| Package | 1KG | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 200kg |
| Update Time: | 2019-09-02 |
Product Details
| Product Name: Butoconazole | CAS No.: 64872-76-0 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: 200kg | Release date: 2019/09/02 |
| Product No:: Cindy 42 |
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Product Name:
Butoconazole
Synonyms:
BUTOCONAZOLE;Butooonazole;BUTONAZOLE;1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)sulfanyl-butyl]imidazole;(±)-1-[4-(4-Chlorophenyl)-2-[(2，6-dichlorophenyl)thio]butyl]-1H-imidazole;1-[2-[(2,6-Dichlorophenyl)thio]-4-(4-chlorophenyl)butyl]-1H-imidazole
CAS:
64872-76-0
MF:
C19H17Cl3N2S
MW:
411.78
EINECS:
Product Categories:
VIDAZA
Mol File:
64872-76-0.mol
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Butoconazole Chemical Properties
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Melting point
68-70.5°
CAS DataBase Reference
64872-76-0(CAS DataBase Reference)
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Safety Information
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MSDS Information
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Butoconazole Usage And Synthesis
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Uses
antineoplastic, pyrimidine antimetabolite
Definition
ChEBI: A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to the nitrogen is substituted by a 4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl group. An antifungal agent, it is used as its nitrate sa t in gynaecology for treatment of vulvovaginal infections caused by Candida species, particularly Candida albicans.
Brand name
Femstat (Roche);Femstat 3 (Bayer); Gynazole-1 (KV Pharmaceutical).
Enzyme inhibitor
This fungicide (FW = 411.78 g/mol; CAS 64872-77-1), also known as Femstat?, Femstat-3?, Gynazole-1?, and systematically as 1-[4- (4- chlorophenyl) -2-[ (2,6-dichlorophenyl) -sulfanyl]butyl]-1H-imidazole (* = chiral center), is believed to inhibit steroid synthesis, targeting the conversion of lanosterol to ergosterol and modifying membrane composition/function. At 80 μM, butoconazole was strictly fungistatic against early stationary-phase Candida albicans cells. During early log- phase growth, butoconazole were highly lethal at 20 μM. In 1995, butoconazole was approved for treatment of vaginal yeast infections.
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Butoconazole Preparation Products And Raw materials
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Raw materials
tert-Butanol-->4-Chlorobenzyl chloride-->2,6-DICHLOROTHIOPHENOL
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Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com