Mubritinib
Price | $3 |
Package | 3KG |
Min. Order: | 1KG |
Supply Ability: | 100kg |
Update Time: | 2019-08-08 |
Product Details
Product Name: Mubritinib | CAS No.: 366017-09-6 |
Min. Order: 1KG | Purity: 99% |
Supply Ability: 100kg | Release date: 2019/08/08 |
Product Model: windy |
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Mubritinib Basic information
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Product Name:
Mubritinib
Synonyms:
(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165);MUBRITINIB;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;Mubritinib 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;(E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole;TAK 165;Mubritinib(TAK 165)
CAS:
366017-09-6
MF:
C25H23F3N4O2
MW:
468.47
EINECS:
Product Categories:
Inhibitors
Mol File:
366017-09-6.mol
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Mubritinib Chemical Properties
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Melting point
158.0 to 162.0 °C
storage temp.
Store at +4°C
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Safety Information
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MSDS Information
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Mubritinib Usage And Synthesis
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Uses
Treatment of cancer.
Biological Activity
Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC 50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC 50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com