Seratrodast
| Price | $7 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Seratrodast | CAS No.: 112665-43-7 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
JD607
| Product Name: | Seratrodast |
| Synonyms: | Seratrodast AA 2414;benzeneheptanoic acid, -(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-;(+-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoicacid;aa-2414;beta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-bezeneheptanoicaci;5-(2,4,5-trimethyl-3,6,-dioxo-1,4-cyclohexadien-1-yl)benzeneheptanoic acid;7-(3,5,6-trimethy1-1,4-benzoquinon-2-y1)-7-phenylheptanoic acid;7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-1-cyclohexa-1,4-dienyl)heptanoic acid |
| CAS: | 112665-43-7 |
| MF: | C22H26O4 |
| MW: | 354.44 |
| EINECS: | 692-169-8 |
| Product Categories: | ZAGAM;API;Heterocyclic Compounds;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 112665-43-7.mol |
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| Seratrodast Chemical Properties |
| Melting point | 118-120°C |
| storage temp. | Store at +4°C |
| Merck | 14,8459 |
| CAS DataBase Reference | 112665-43-7(CAS DataBase Reference) |
| Safety Information |
| RTECS | DA1600050 |
| MSDS Information |
| Seratrodast Usage And Synthesis |
| Description | Seratrodast, a novel benzoquinone derivative, is the first thromboxane A2 (TxA2) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA2, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA2 mimic and by a variety of spasmogenic prostanoids including PGF2α, PGD2 and 9α,11β-PGF2. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer. |
| Chemical Properties | Pale Orange Solid |
| Originator | Takeda (Japan) |
| Uses | antibacterial |
| Uses | Thromboxane A2-receptor antagonist. Antiasthmatic |
| Brand name | Bronica |
| Biological Activity | Thromboxane A 2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA 2 mimetic in guinea pigs. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com