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Postion:Product Catalog >Organic Chemistry>Organic fluorine compound>Fluoro-benzoic acid series>4-Fluorobenzoic acid
4-Fluorobenzoic acid
  • 4-Fluorobenzoic acid

4-Fluorobenzoic acid

Price $1
Package 1kg
Min. Order: 1g
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: 4-Fluorobenzoic acid CAS No.: 456-22-4
Min. Order: 1g Purity: 99%
Supply Ability: 100KG Release date: 2019/07/06
PRODUCT:: AD68
4-Fluorobenzoic acid Basic information
Description Reference
Product Name: 4-Fluorobenzoic acid
Synonyms: 4-FLUOROBENZOIC ACID;AKOS 92636;PFBA;P-FLUOROBENZOIC ACID;TIMTEC-BB SBB008568;RARECHEM AL BO 0053;4-fluoro-benzoicaci;Benzoic acid, p-fluoro-
CAS: 456-22-4
MF: C7H5FO2
MW: 140.11
EINECS: 207-259-0
Product Categories: Fluorin-contained Benzoic acid series;Benzene derivatives;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Fluorobenzene;API intermediates;Carboxylic Acids;Phenyls & Phenyl-Het;C7;Carbonyl Compounds;carboxylic acid| alkyl Fluorine
Mol File: 456-22-4.mol
Article illustration
 
4-Fluorobenzoic acid Chemical Properties
Melting point  184 °C
density  1.479
storage temp.  Store below +30°C.
solubility  alcohol: soluble
form  Crystalline Powder
pka 4.15(at 25℃)
color  White to slightly yellow
Water Solubility  Soluble in alcohol, hot water, methanol, and ether. Very slightly soluble in cold water.
Merck  14,4171
BRN  1906922
CAS DataBase Reference 456-22-4(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 4-fluoro-(456-22-4)
EPA Substance Registry System Benzoic acid, 4-fluoro-(456-22-4)
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-41-36/37/38
Safety Statements  26-39-24/25-22-37/39-36
WGK Germany  3
Hazard Note  Irritant
TSCA  T
HazardClass  IRRITANT
HS Code  29163900
4-Fluorobenzoic acid Usage And Synthesis
Description 4-Fluorobenzoic acid is used as an intermediate in organic synthesis. For instance, it is used to synthesize N-cuccinimidyl 4-[18F]-fluorobenzoate, which is used for the 18F labeling of antibodies. It has been used in high resolution charge density study.
Reference AG. Vaidyanathan, M. R. Zalutsky, Improved Synthesis of N-Succinimidyl 4-[18F]Fluorobenzoate and Its Application to the Labeling of a Monoclonal Antibody Fragment, Bioconjuate Chemistry, 1994, vol. 5, pp. 352-356
Chemical Properties white to light yellow crystal powder
Definition ChEBI: A fluorobenzoic acid carrying a fluoro substituent at position 4.
Purification Methods Crystallise the acid from 50% aqueous EtOH, then purify it by zone melting or vacuum sublimation at 130-140o. [Beilstein 9 H 333, 9 III 1327, 9 IV 953.]

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Since: 2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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