5-Methoxytryptophol NEW
Price | $26 | $30 | $50 |
Package | 10mg | 25mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-07 |
Product Details
Product Name: 5-Methoxytryptophol | CAS No.: 712-09-4 |
Purity: 98.53% | Supply Ability: 10g |
Release date: 2024/11/07 |
Product Introduction
Bioactivity
名稱 | 5-Methoxytryptophol |
描述 | 5-Methoxytryptophol (2-(5-Methoxy-1H-indol-3-yl)ethanol) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species. |
體外活性 | In MC3T3-E1 cells, most of the 5-methoxytryptophol doses reduced slightly the metabolic activity of osteoblasts. After 14 days of cell culture, Rankl mRNA levels were decreased. 5-methoxytryptophol also induced a high osteocalcin secretion and mineralization capacity. In RAW264.7 cells, 5-methoxytryptophol decreased the number of osteoclast formed and its activity. 5-methoxytryptophol promoted activation of the ERK1/2 pathway through the phosphorylation of ERK, while LUZ addition suppressed this effect. In conclusion, 5-methoxytryptophol inhibits osteoclastogenesis and promoting osteoblast differentiation[3]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 88 mg/mL (460.18 mM) |
關(guān)鍵字 | Endogenous Metabolite | Inhibitor | 5 Methoxytryptophol | 5-Methoxytryptophol | 5Methoxytryptophol | inhibit |
相關(guān)產(chǎn)品 | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Vanillin | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid | Oleic acid |
相關(guān)庫 | 經(jīng)典已知活性庫 | 天然產(chǎn)物庫 | 高通量篩選天然產(chǎn)物庫 | Ro5類藥天然產(chǎn)物庫 | 人內(nèi)源代謝化合物庫 | 人內(nèi)源代謝化合物庫 Plus | 已知活性化合物庫 | 人代謝物化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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