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Postion:Product Catalog >4SC-203
4SC-203
  • 4SC-203

4SC-203 NEW

Price $68 $163 $263
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: 4SC-203 CAS No.: 895533-09-2
Purity: 99.73% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱4SC-203
描述4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity. 4SC-203 exhibits unique selectivity for Flt3, Flt3 mutants, Axl, Alk, Fak, VEGF-R2, and Trk receptors in the low nM range.
體外活性4SC-203 exhibits unique selectivity in the low nM range for Flt3, Flt3 mutants, Axl, Alk, Fak, VEGF-R2, and Trk receptors.[1]
體內(nèi)活性In preclinical studies, 4SC-203 demonstrated significant antitumor activity in in vivo models relevant to acute myeloid leukemia. In a first-in-human study in healthy volunteers, 4SC-203 was shown to be well tolerated across the concentration range studied and to have a favorable pharmacokinetic profile.[1]
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : Slightly soluble
關(guān)鍵字tumor | antineoplastic | Fms like tyrosine kinase 3 | Vascular endothelial growth factor receptor | FLT3 | 4SC203 | 4SC 203 | FLT3/STK1 | 4SC-203 | inhibit | VEGFR | Inhibitor | Cluster of differentiation antigen 135 | multikinase | CD135
相關(guān)產(chǎn)品UNC2025 | Gilteritinib | Fedratinib | Nintedanib | Sunitinib | Sunitinib Malate | Sorafenib | Tandutinib | Pexidartinib | KW-2449 | Sorafenib tosylate | SGI-1776
相關(guān)庫經(jīng)典已知活性庫 | 酪氨酸激酶分子庫 | 激酶抑制劑庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | NO PAINS 化合物庫 | 已知活性化合物庫 | 抗癌藥物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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