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Postion:Product Catalog >Biochemical Engineering>Natural Products>Capsaicin
Capsaicin
  • Capsaicin

Capsaicin

Price $1
Package 1KG
Min. Order: 1G
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: Capsaicin CAS No.: 404-86-4
Min. Order: 1G Purity: 98%
Supply Ability: 100KG Release date: 2019/07/06

AD68

Capsaicin Basic information
Application in Particular Diseases
Product Name: Capsaicin
Synonyms: (E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;(E)-CAPSAICIN;(E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE;(E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE;CAPSAICIN;CAPSAICINE;CAPSAICIN, NATURAL;FEMA 3404
CAS: 404-86-4
MF: C18H27NO3
MW: 305.41
EINECS: 206-969-8
Product Categories: INORGANIC & ORGANIC CHEMICALS;Anilines, Aromatic Amines and Nitro Compounds;Miscellaneous Natural Products;Natural Plant Extract;Intermediates & Fine Chemicals;Pharmaceuticals;Vanilloid/TRPV channel;Amines;Aromatics;Alkaloid;Amides;Bioactive Small Molecules;Building Blocks;Carbonyl Compounds;C-CH;Cell Biology;Chemical Synthesis;Nutrition Research;Organic Building Blocks;Phytochemicals by Chemical Classification;Phytochemicals by Plant (Food/Spice/Herb);Zingiber officinale (Ginger);API;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;NEURELAN;natural product;food additive;Inhibitors
Mol File: 404-86-4.mol
Article illustration
 
Capsaicin Chemical Properties
Melting point  62-65 °C(lit.)
Boiling point  210-220 C
density  1.1037 (rough estimate)
refractive index  1.5100 (estimate)
FEMA  3404 | CAPSAICIN
Fp  113 °C
storage temp.  2-8°C
solubility  H2O: insoluble
Water Solubility  insoluble
Merck  14,1768
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 404-86-4(CAS DataBase Reference)
EPA Substance Registry System 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl-, (6E)-(404-86-4)
 
Safety Information
Hazard Codes  T,T+
Risk Statements  25-37/38-41-42/43-36/37/38
Safety Statements  22-26-28-36/39-45-36/37/39
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  RA8530000
10-21
HazardClass  6.1(a)
PackingGroup  II
Hazardous Substances Data 404-86-4(Hazardous Substances Data)
Capsaicin Usage And Synthesis
Application in Particular Diseases In Osteoarthritis:
  • Capsaicin, an extract of red peppers that causes release and ultimately depletion of substance P from nerve fibers, has been beneficial in providing pain relief in OA when applied topically over affected joints. It may be used alone or in combination with oral analgesics or NSAIDs.
  • To be effective, capsaicin must be used regularly, and it may take up to 2 weeks to work. It is well tolerated, but some patients experience temporary burning or stinging at the site of application. Patients should be warned not to get the cream in their eyes or mouth and to wash their hands after application.
  • Application of the cream, gel, or lotion is recommended four times daily, but tapering to twice-daily application may enhance long-term adherence with adequate pain relief.
Chemical Properties Off-White Crystalline Solid
Uses A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Uses K channel blocker; multiple sclerosis therapy
Uses analgesic (topical), depletes Substance P, neurotoxic
Uses Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Uses Capsaicin is used in many topical ointments used to relieve the pain of peripheral neuropathy (treatment of pain in the nerve endings near the surface of the skin).
Uses As a tool in neurobiological research.
Biological Activity Prototypic vanilloid receptor agonist (pEC 50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets. Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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