4-Phenylbutyric acid NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-07-29 |
Product Details
| Product Name: 4-Phenylbutyric acid | CAS No.: 1821-12-1 |
| EC-No.: 217-341-8 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 50000KG/month |
| Release date: 2023/07/29 |
| CAS: | 1821-12-1 |
| MF: | C10H12O2 |
| MW: | 164.2 |
| EINECS: | 217-341-8 |
| Product Categories: | Aromatics;Intermediates & Fine Chemicals;Organic acids;Carbonyl Compounds;Carboxylic Acids;Pharmaceuticals;Pharmaceutical Raw Materials;C10 |
| Mol File: | 1821-12-1.mol |
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| 4-Phenylbutyric acid Chemical Properties |
| Melting point | 49-51 °C(lit.) |
| Boiling point | 165 °C10 mm Hg(lit.) |
| density | 1.0326 (rough estimate) |
| refractive index | 1.5405 (estimate) |
| Fp | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 5.3g/l |
| pka | 4.76(at 25℃) |
| form | Crystalline Powder |
| color | White to slightly yellow |
| Water Solubility | 5.3 g/L at 40 oC |
| BRN | 638180 |
| InChIKey | OBKXEAXTFZPCHS-UHFFFAOYSA-N |
| LogP | 2.420 |
| CAS DataBase Reference | 1821-12-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Phenylbutanoic acid(1821-12-1) |
| EPA Substance Registry System | 4-Phenylbutyric acid (1821-12-1) |
| 4-Phenylbutyric acid Usage And Synthesis |
| Chemical Properties | 4-Phenylbutyric acid is white to slightly yellowish crystalline powder. It is slightly soluble in chloroform and methanol. Its solubility in water is 5.3 g/l (at 40 °C). |
| Uses | 4-Phenylbutyric acid is used as a chemical chaperone involved in protein-folding disorders. It is involved in the synthesis of dyes and an active pharmaceutical ingredient intermediate. |
| Definition | 4-Phenylbutyric acid is a monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apopto is in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation. |
| Preparation | 4-phenylbutyric acid is obtained by the reaction of benzene with butyrolactone in the presence of aluminum chloride, followed by neutralization with base. Synthesis of 4-phenylbutyric acid |
| Application | 4-Phenylbutyric acid (4-PBA) is used in the treatment of urea cycle disorders under the trade name Buphenyl. 4-PBA has been used as a selective inhibitor of endoplasmic reticulum stress (ERS). 4-Phenylbutyric acid is used as organic intermediates. It can also be used as a reactant in the synthesis of: 1-Tetralone using Lewis acid catalyst. 4,N-diphenylbutyramide. |
Product picture
Packing &shipping&Payment
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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Japan
- Since: 2017-12-08
- Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
13288715578
sales@hbmojin.com