3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone NEW
| Price | $89 | $222 | $328 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-07 |
Product Details
| Product Name: 3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone | CAS No.: 1178-24-1 |
| Purity: 99.69% | Supply Ability: 10g |
| Release date: 2024/11/07 |
Product Introduction
Bioactivity
| 名稱 | 3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone |
| 描述 | 3,5,6,7,8,3',4'-Heptemthoxyflavone exhibits neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging, and photoprotective effects; it inhibits collagenase activity, induces type I procollagen synthesis in HDFn cells, and combats nitric oxide (NO) carcinogenesis. |
| 體外活性 | 3,5,6,7,8,3',4'-Heptamethoxyflavone (HMF), extracted from C. unshiu peels using ethanol extraction and hexane fractionation, inhibited collagenase activity and increased type I procollagen content in UV-induced human dermal fibroblast neonatal (HDFn) cells. HMF also suppressed matrix metalloproteinases 1 (MMP-1) expression and induced type I procollagen protein expression in these cells. Additionally, HMF inhibited UVB-induced phosphorylation of MAPK cascade signaling components—ERK, JNK, and c-Jun—thereby reducing MMP-1 expression. Furthermore, HMF modulated the TGF-β/Smad signaling pathway by inducing Smad3 and suppressing Smad7 protein expressions in a dose-dependent manner in UV-induced HDFn cells. |
| 存儲條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 12 mg/mL (27.75 mM) |
| 關(guān)鍵字 | inhibit | 3,5,6,7,8,3',4'-Heptemthoxyflavone | Inhibitor | 3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone | 3,?5,?6,?7,?8,?3',?4' ?Heptemthoxyflavone | 3,?5,?6,?7,?8,?3',?4'?Heptemthoxyflavone |
| 相關(guān)庫 | 中藥單體化合物庫 | 經(jīng)典已知活性庫 | 植物來源化合物庫 | 天然產(chǎn)物庫 | 中藥抗炎分子庫 | 神經(jīng)保護化合物庫 | 高通量篩選天然產(chǎn)物庫 | 抗癌活性化合物庫 | 藥食同源庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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