2-Thiobarbituric acid NEW
Price | Get Latest Price |
Package | 25KG |
Min. Order: | 1KG |
Supply Ability: | 50000KG/month |
Update Time: | 2023-11-07 |
Product Details
Product Name: 2-Thiobarbituric acid | CAS No.: 504-17-6 |
EC-No.: 207-985-8 | Min. Order: 1KG |
Purity: 99% | Supply Ability: 50000KG/month |
Release date: 2023/11/07 |
CAS: | 504-17-6 |
MF: | C4H4N2O2S |
MW: | 144.15 |
EINECS: | 207-985-8 |
Product Categories: | Heterocyclic Compounds;Aromatics;PYRIMIDINE;Bases & Related Reagents;Nucleotides;Sulfur & Selenium Compounds;Aromatics Compounds;Building Blocks;C4 to C5;Chemical Synthesis;Heterocyclic Building Blocks;Pyrimidines;Heterocycle-Pyrimidine series;504-17-6 |
Mol File: | 504-17-6.mol |
2-Thiobarbituric acid Chemical Properties |
Melting point | 245 °C (dec.)(lit.) |
density | 1.451 (estimate) |
refractive index | 1.7690 (estimate) |
storage temp. | Inert atmosphere,2-8°C |
solubility | 50g/l slightly soluble |
pka | 3.96±0.20(Predicted) |
form | Liquid |
color | Clear colorless |
PH | 1.7-1.9 (10g/l, H2O, 20℃) |
Water Solubility | <6 g/L (20 oC) |
BRN | 120663 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | RVBUGGBMJDPOST-UHFFFAOYSA-N |
CAS DataBase Reference | 504-17-6(CAS DataBase Reference) |
NIST Chemistry Reference | 4,6(1H,5h)-pyrimidinedione, dihydro-2-thioxo-(504-17-6) |
EPA Substance Registry System | 4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo- (504-17-6) |
2-Thiobarbituric acid Usage And Synthesis |
Chemical Properties | Off-White to Yellow Powder. soluble in hot water, alcohol, ether, alkali and sodium carbonate solution, slightly soluble in water. |
Uses | 4,6-Dihydroxy-2-mercaptopyrimidine can be used to quantitate lipopolysaccharides, carrageenan, and sialic acids, and to detect lipid hydroperoxides and lipid oxidation. |
Uses | 2-Thiobarbituric acid has been used to measure malondialdehyde (MDA) in lipid peroxidation assay. |
Preparation | 2-thiobarbituric acid was synthesized by the reaction of diethyl malonate with thiourea. Dissolve thiourea in methanol, add sodium methoxide and diethyl malonate, heat under reflux for 4-5h, then distill under reduced pressure to recover methanol to the end, and add hydrochloric acid to acidify to pH 1-2 after cooling. After standing overnight, thiobarbituric acid crystals were precipitated, filtered, and recrystallized with water to obtain the pure product. |
Definition | ChEBI: 2-thiobarbituric acid is a barbiturate, the structure of which is that of barbituric acid in which the oxygen at C-2 is replaced by sulfur. It has a role as a reagent and an allergen. |
General Description | 2-Thiobarbituric acid is a molecule made up of heteroatoms: nitrogen, sulphur and oxygen. |
Biochem/physiol Actions | 2-Thiobarbituric acid (TBA) is useful to quantitate lipopolysaccharides, carrageenan, and sialic acids. It is also used to detect lipid hydroperoxides and lipid oxidation. It has applications in the field of medicine and biochemistry. TBA may possess the ability to prevent metal corrosion. |
Purification Methods | Crystallise it from water. [Beilstein 24 H 476, 24 I 414, 24 II 275, 24 III/IV 1884.] |
Packing &shipping&Payment
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms) | 1 - 10000 | >10000 |
Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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