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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyrimidines>Mercaptopyrimidine>2-Thiobarbituric acid
2-Thiobarbituric acid
  • 2-Thiobarbituric acid
  • 2-Thiobarbituric acid
  • 2-Thiobarbituric acid
  • 2-Thiobarbituric acid
  • 2-Thiobarbituric acid

2-Thiobarbituric acid NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-11-07

Product Details

Product Name: 2-Thiobarbituric acid CAS No.: 504-17-6
EC-No.: 207-985-8 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/11/07

CAS:504-17-6
MF:C4H4N2O2S
MW:144.15
EINECS:207-985-8
Product Categories:Heterocyclic Compounds;Aromatics;PYRIMIDINE;Bases & Related Reagents;Nucleotides;Sulfur & Selenium Compounds;Aromatics Compounds;Building Blocks;C4 to C5;Chemical Synthesis;Heterocyclic Building Blocks;Pyrimidines;Heterocycle-Pyrimidine series;504-17-6
Mol File:504-17-6.mol
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2-Thiobarbituric acid Chemical Properties
Melting point 245 °C (dec.)(lit.)
density 1.451 (estimate)
refractive index 1.7690 (estimate)
storage temp. Inert atmosphere,2-8°C
solubility 50g/l slightly soluble
pka3.96±0.20(Predicted)
form Liquid
color Clear colorless
PH1.7-1.9 (10g/l, H2O, 20℃)
Water Solubility <6 g/L (20 oC)
BRN 120663
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyRVBUGGBMJDPOST-UHFFFAOYSA-N
CAS DataBase Reference504-17-6(CAS DataBase Reference)
NIST Chemistry Reference4,6(1H,5h)-pyrimidinedione, dihydro-2-thioxo-(504-17-6)
EPA Substance Registry System4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo- (504-17-6)
2-Thiobarbituric acid Usage And Synthesis
Chemical PropertiesOff-White to Yellow Powder. soluble in hot water, alcohol, ether, alkali and sodium carbonate solution, slightly soluble in water.
Uses4,6-Dihydroxy-2-mercaptopyrimidine can be used to quantitate lipopolysaccharides, carrageenan, and sialic acids, and to detect lipid hydroperoxides and lipid oxidation.
Uses2-Thiobarbituric acid has been used to measure malondialdehyde (MDA) in lipid peroxidation assay.
Preparation2-thiobarbituric acid was synthesized by the reaction of diethyl malonate with thiourea. Dissolve thiourea in methanol, add sodium methoxide and diethyl malonate, heat under reflux for 4-5h, then distill under reduced pressure to recover methanol to the end, and add hydrochloric acid to acidify to pH 1-2 after cooling. After standing overnight, thiobarbituric acid crystals were precipitated, filtered, and recrystallized with water to obtain the pure product.
DefinitionChEBI: 2-thiobarbituric acid is a barbiturate, the structure of which is that of barbituric acid in which the oxygen at C-2 is replaced by sulfur. It has a role as a reagent and an allergen.
General Description2-Thiobarbituric acid is a molecule made up of heteroatoms: nitrogen, sulphur and oxygen.
Biochem/physiol Actions2-Thiobarbituric acid (TBA) is useful to quantitate lipopolysaccharides, carrageenan, and sialic acids. It is also used to detect lipid hydroperoxides and lipid oxidation. It has applications in the field of medicine and biochemistry. TBA may possess the ability to prevent metal corrosion.
Purification MethodsCrystallise it from water. [Beilstein 24 H 476, 24 I 414, 24 II 275, 24 III/IV 1884.]

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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