2-Hydroxy-3-methoxy chalcone NEW
Price | $195 | $430 | $636 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: 2-Hydroxy-3-methoxy chalcone | CAS No.: 7146-86-3 |
Purity: 98% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | 2-Hydroxy-3-methoxy chalcone |
描述 | 2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer. |
體外活性 | 2'-hydroxy-3'-methoxychalcone (TJ3) (10 μM and 25 μM ) significantly reduced the release of ICAM-1 by SW480 cancer cells. It did not have a significant effect on VCAM-1 released by SW480 and SW620 cancer cell lines. However, it demonstrated a significant dose-dependent reduction in the concentration of MIF on SW480 cells. Additionally, TJ3 at a concentration of 25 μM significantly decreased IL-8 secretion by both SW480 and SW620 cancer cells. These results indicate that the tested TJ3 exhibits a modulating effect on colon cancer cells.[1] |
存儲(chǔ)條件 | Shipping with blue ice. |
溶解度 | DMSO : 45 mg/mL (176.97 mM) |
相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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