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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyridine compound>Methylpyridine>2-Chloro-1-methylpyridinium iodide
2-Chloro-1-methylpyridinium iodide
  • 2-Chloro-1-methylpyridinium iodide
  • 2-Chloro-1-methylpyridinium iodide
  • 2-Chloro-1-methylpyridinium iodide
  • 2-Chloro-1-methylpyridinium iodide
  • 2-Chloro-1-methylpyridinium iodide

2-Chloro-1-methylpyridinium iodide NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-10-12

Product Details

Product Name: 2-Chloro-1-methylpyridinium iodide CAS No.: 14338-32-0
EC-No.: 238-288-7 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/10/12

CAS:14338-32-0
MF:C6H7ClIN
MW:255.48
EINECS:238-288-7
Product Categories:Coupling Reactions (Peptide Synthesis);Peptide Synthesis;Pyridinium Compounds;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;C6Heterocyclic Building Blocks;Heterocyclic Compounds;Biochemistry;Condensation & Active Esterification;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines
Mol File:14338-32-0.mol
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2-Chloro-1-methylpyridinium iodide Chemical Properties
Melting point 200 °C (dec.) (lit.)
density 1.7949 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Crystalline Powder and/or Chunks
color Yellow
Water Solubility soluble
Sensitive Moisture & Light Sensitive
Merck 14,6301
BRN 3572320
Exposure limitsACGIH: TWA 0.01 ppm
InChIKeyABFPKTQEQNICFT-UHFFFAOYSA-M
CAS DataBase Reference14338-32-0(CAS DataBase Reference)
EPA Substance Registry System2-Chloro-1-methylpyridinium iodide (14338-32-0)
2-Chloro-1-methylpyridinium iodide Usage And Synthesis
Chemical Propertiesyellow crystalline solid
UsesCondensation reagent for the synthesis of esters and ketenes, and for the kinetic resolution of carboxylic acids and alcohols.
Uses2-Chloro-1-methylpyridinium iodide is a reagent in a wide variety of dehydrative coupling reactions. It is also used to form carboxylate esters from acids and alcohols, carboxamides from acids and amines, lactones from -hydroxy acids and carbodiimides from N,N-disubstituted thioureas.
General Description2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC.
Purification MethodsPurify it by dissolving in EtOH and adding dry Et2O. The solid is washed with Me2CO and dried at 20o/0.35mm. Store it in the dark. Attempted recrystallisation from Me2CO/EtOH/pet ether (b 40-60o) causes some exchange of the Cl substituent by I. The picrate has m 106-107o, and the perchlorate has m 212-213o. [Jones et al. J Am Chem Soc 111 1157 1989, UV and solvolysis: Barlin & Benbow J Chem Soc, Perkin Trans 2 790 1974, Beilstein 20/5 V 405.]

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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