2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine NEW
Price | $50 | $1 |
Package | 1KG | 1000KG |
Min. Order: | 1KG |
Supply Ability: | g-kg-tons, free sample is available |
Update Time: | 2023-12-23 |
Product Details
Product Name: 2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine | CAS No.: 3605-01-4 |
Min. Order: 1KG | Purity: 99% |
Supply Ability: g-kg-tons, free sample is available | Release date: 2023/12/23 |
Lead time: In stock | Packaging: bottle/drum/bucket/IBC, as request. |
Delivery: By sea, by air, by express | Origin: Manufacturer |
1. Product information
Product Name: | 2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine |
Synonyms: | PIRIBEDIL;Piribendyl;2-(4-(benzo[d][1,3]dioxol-5-ylMethyl)piperazin-1-yl)pyriMidine;1-(2-Pyrimidyl)-4-piperonylpiperazine;PIRIBEDIL(FORR&DONLY0;PIRIBEDIOL;ET-495;EU-4200 |
CAS: | 3605-01-4 |
MF: | C16H18N4O2 |
MW: | 298.34 |
EINECS: | 222-764-6 |
Product Categories: | Isotope labelled API;API |
Mol File: | 3605-01-4.mol |
2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine Chemical Properties |
Melting point | 98° |
Boiling point | 439.76°C (rough estimate) |
density | 1.1183 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
pka | 7.17±0.10(Predicted) |
form | Solid |
color | White |
2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine Usage And Synthesis |
Chemical Properties | White Solid |
Originator | Trivastal, Eutherapie ,France,1969 |
Uses | Piribedil is an antiparkisonian agent that acts as a dopamine agonist. Piribedil also displays α2-adrenergic antagonist properties. Piribedil has also been shown to counteract age-related memory impai rment by improving memory and attention as well as increasing the velocity of psychomotor reactions and lability of nervous processes. |
Uses | Piribedil is an antiparkisonian agent that acts as a dopamine agonist. Piribedil also displays α2-adrenergic antagonist properties. Piribedil has also been shown to counteract age-related memory impairment by improving memory and attention as well as increasing the velocity of psychomotor reactions and lability of nervous processes. |
Definition | ChEBI: 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine is a N-arylpiperazine. |
Manufacturing Process | To a solution of 21 g of 1-(3':4'-methylenedioxybenzyl)-piperazine in solution in 300 cc of anhydrous xylene there were added 28 g of anhydrous potassium carbonate and then 11.3 g of 2-chloropyrimidine. The suspension was then heated for 9 hours at boiling point (130°C). After this time, the mixture was cooled and extracted several times with 10% hydrochloric acid. The acid solution obtained was washed with ether and then rendered alkaline with potassium carbonate; the oily product which was separated was extracted with chloroform and this, after drying with potassium carbonate and evaporation, gave an oily residue weighing 20 g. By dissolution in boiling ethanol and crystallization, 15 g of crystals melting at 96°C were recovered. |
Therapeutic Function | Vasodilator |
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Email address : elin@fdachem.com
Mob: 86 13613820652
WhatsApp/Skype/Wechat/LINE: 86 13613820652
Company Profile Introduction
Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.
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- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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