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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Darunavir
Darunavir
  • Darunavir
  • Darunavir
  • Darunavir

Darunavir

Price $1
Package 10g
Min. Order: 10g
Supply Ability: 1000kg
Update Time: 2022-12-29

Product Details

Product Name: Darunavir CAS No.: 206361-99-1
EC-No.: 606-590-1 Min. Order: 10g
Purity: 99.5% Supply Ability: 1000kg
Release date: 2022/12/29

No Customs Issues, Safe Shipping 99% Darunavir Reached Safely From China Factory 206361-99-1


Product description


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Usage And Synthesis


Darunavir is the latest weapon in the arsenal of agents to combat human immunodeficiency virus type 1(HIV-1). As an HIV-1 protease inhibitor, its mechanism of action involves blocking the cleavage of the gag and gag–pol polyproteins into functional proteins essential for the production of infectious progeny virus; the result is the production of immature, noninfectious viral particles. Compared to predecessor HIV protease inhibitors, darunavir retains activity against resistant stains, a critical factor with the continual emergence of multidrug- resistant (MDR) mutants. Despite experiencing a 13-fold reduction in binding to MDR HIV-1 protease, this binding is 1.5 orders of magnitude tighter than the first-generation protease inhibitors. Furthermore, darunavir exhibits less than a 10-fold decrease in susceptibility in cell culture against 90% of 3309 clinical isolates resistant to amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, and tipranavir. In contrast, darunavir-resistant viruses display limited susceptibility to only tipranavir, suggesting limited cross-resistance between these two protease inhibitors. To avoid the issues of the peptide-based protease inhibitors, darunavir has evolved from a structure-based design effort to minimize peptidic features and reduce molecular weight and complexity.    


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Our Service

1.Cooperate with research institutions, we strictly control the process from raw material to finished product.


2.We can provide the reasonable price, high quality products and prompt shipment.

3.We can send the goods to your delivery address directly. It is relatively safe and fast. 

4.Quick and clear response to customers questions, we’ll treat every email and message within 24 hours usually much faster.

5.We can provide you a discount if you place a substantial order with us.

6.Products can be packaged and company logo can be customized according to customer requirements.

 

Delivery


1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitateyou track the express.

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FAQ


Q1: Can i get some samples?
A: Yes, we can supply the sample, but the shipping cost be paid by ourcustomers.


Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosedour bank information. Payment by T/T, Western Union or Paypal.


Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay theshipping cost or arrange a courier to us and take the samples. You cansend us your product specifications and requests,we will manufacture theproducts according to your requests.

Q4:What's your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g onthe condition that sample charge is 100% paid.


Q5: How about delivery lead time?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chineseholiday not included)


Q6: Do You Ship Over The Weekend?
We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcelsover the weekend. The packages can be shipped out normally before 12:00a.m in Beijing time if you choose to ship by TNT or FedEx.


Company Profile Introduction

Guangzhou Biocar Biotechnology Co., Ltd., formerly known as Guangdong Yangye Pharmaceutical Factory established in 2005, which is affiliated to Wuhan Biocar Group. With the rise of Internet +, company′s business process is accelerating. The company′s board of directors has decided to establish Guangzhou Yangye Biotechnology Co., Ltd. At the end of 2016. Guangzhou Biocar Biotechnology Co., Ltd. is located near Zhujiang New Town, Tianhe District, one of the prosperous areas in Guangzhou city. This helps facilitate business negotiations at home and abroad. It is a high-tech enterprise centered in Guangdong Province, radiating across our country and facing the world. And it is mainly engaged in the research, development and sales of new chemical raw materials, the custom synthesis and import and export of pharmaceutical intermediates and APIs, the agency sales of pharmaceutical chemicals, the research and development, production and sales of flavors, fragrances and chemical raw materials. Its factory covers an area of more than 4, 000 acres and has more than 600 employees. Guangzhou Biocar Biotechnology has a production base for deep processing of feed additives and veterinary drug intermediates based on main pharmaceutical intermediates. It has always adhered to the tenet of "Being faithful, cultivating harmony and achieving win-win cooperation" and treats every customer sincerely.

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  • Since: 2017-01-06
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INQUIRY
楊樂
+86-13397196830
carrie@gzbiocar.cn