Efavirenz
Price | Get Latest Price | ||
Package | 1Kg/Bag | 25Kg/Bag | 100Kg/Bag |
Min. Order: | 0.1Kg/Bag |
Supply Ability: | 20 tons |
Update Time: | 2025-01-03 |
Product Details
Product Name: Efavirenz | CAS No.: 154598-52-4 |
EC-No.: 620-492-6 | Min. Order: 0.1Kg/Bag |
Purity: USP | Supply Ability: 20 tons |
Release date: 2025/01/03 |
Product Information
Product Name | Pharmaceutical Intermediate CAS 154598-52-4 Efavirenz for Anti-Allergic |
Appearance | powder |
cas | 154598-52-4 |
Assay | 90% |
Keywords | Efavirenz; API Efavirenz powder;Efavirenz Medicine |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
Usage
What is Efavirenz ?
Efavirenz D5 (Sustiva)84 is also mandated for use with at leasttwo other antiretroviral agents. The compound is morethan 99% protein bound, and CSF concentrations exceedthe free fraction in the serum. Metabolism occurs in theliver. The half-life of a single dose of Efavirenz D5 is 52 to 76hours, and 40 to 55 after multiple doses (the drug inducesits own metabolism). Peak concentration is achieved in 3to 8 hours. Elimination is 14% to 34% in urine (as metabolites)and 16% to 41% in feces (primarily as Efavirenz D5).The oral dosage form is supplied as a capsule.
Function of Efavirenz
Efavirenz is one of the most commonly prescribed antiretroviral medications in the world. Several large randomized, controlled trials[RCTs] have demonstrated the superior ability of efavirenz to suppress the HIV virus when used as part of a 3-drug cocktail[2]. The introduction of Atripla in 2006 combined efavirenz and two other agents into a single pill, once-daily formulation. This formulation was more convenient and better tolerated than alternatives, and thus resulted in improved adherence to antiretroviral medications[3]. However, neuropsychiatric side effects associated with efavirenz have been reported to occur in 40-50% of patients and represent one of the limiting factors of this regime
Application of Efavirenz
For use in combination treatment of HIV infection (AIDS)
COA
Test items | Specification |
Appearance | White to off-white crystalline powder |
solubility | 50mg/ml in Methanol Solvent,clear |
Water | ≤0.5% |
Related substance | Impurity A ≤0.15% |
Impurity B ≤0.40% | |
Impurity C ≤0.10% | |
Impurity D ≤0.10% | |
Impurity E ≤0.10% | |
Impurity I ≤0.25% | |
Impurity K ≤0.10% | |
Other unknown individual impurity ≤0.10% | |
Total impurities ≤0.10% | |
Isomeride | ≤0.5% |
Heavy Metal | ≤20ppm |
Residue on ignition | ≤0.2% |
Assay | Not less than 98% |
Company Information
Company Profile Introduction
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$35.00/5mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$0.00/200kg |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-10-31 | |
$0.00/1kg |
VIP1Y
|
Shaanxi TNJONE Pharmaceutical Co., Ltd
|
2024-05-07 | |
$15.00/1kg |
Ouhuang Engineering Materials (Hubei) Co., Ltd
|
2024-04-28 | ||
$0.00/25kg |
PNP Biotech Co. Ltd
|
2023-07-12 | ||
$0.00/25KG |
VIP5Y
|
Hebei Mojin Biotechnology Co., Ltd
|
2023-07-04 | |
$100.00/1ml |
Shijiazhuang Gantuo Biotechnology Co., Ltd
|
2023-03-10 | ||
$200.00/1kg |
Hebei Mingeng Biotechnology Co., Ltd
|
2022-11-24 | ||
$32.00/1KG |
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
|
2021-12-16 | ||
$15.00/1KG |
Qiuxian Baitai New Material Co., LTD
|
2021-11-26 |
- Since: 1996-07-16
- Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.