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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>Pimavanserin
Pimavanserin
  • Pimavanserin
  • Pimavanserin
  • Pimavanserin
  • Pimavanserin
  • Pimavanserin

Pimavanserin NEW

Price $650 $550 $350
Package 1Kg/Bag 25Kg/Bag 100Kg/Bag
Min. Order: 1Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-12-23

Product Details

Product Name: Pimavanserin CAS No.: 706779-91-1
EC-No.: 1806241-263-5 Min. Order: 1Kg/Bag
Purity: 99% up, High Density Supply Ability: 20 tons
Release date: 2024/12/23

Product Information 


High Purity Pharmaceutical Grade Antipsychotic Drugs CAS 706782-28-7 Pimavanserin Powder

AppearancePimavanserin
CAS706779-91-1
Assay99%
KeywordsPharmaceutical Pimavanserin;Pimavanserin Raw Material powder;Pimavanserin
Shelf Life24 months when properly stored
StorageKeep in a cool, dry, dark location

Article illustration

Usage 


Function of Pimavanserin

Pimavanserin is the active pharmaceutical ingredient of Nuplazid, which was approved by the FDA in 2016 for the treatment of hallucinations and delusions associated with psychosis in patients suffering from Parkinson's disease.

Application of Pimavanserin

Pimavanserin is the active pharmaceutical ingredient of Nuplazid, which was approved by the FDA in 2016 for the treatment of hallucinations and delusions associated with psychosis in patients suffering from Parkinson's disease. Its exact mechanism of action is unclear. The drug exhibits a combination of inverse agonist and antagonist activity at the serotonin 2A receptors (5-HT2A) and, to a lesser extent, at the 5-HT2C receptors in the central nervous system, which is believed to contribute to its antipsychotic activity. Pimavanserin is absorbed in the gastrointestinal tract and is highly bound to plasma protein (approximately 95%). Following the administration of a single 34-mg dose of pimavanserin, the time to maximum plasma concentration is six hours, the half-life is approximately 57 h and the mean (standard deviation, SD) apparent volume of distribution is 2,173 (307) L. Pimavanserin is metabolized in the liver predominantly by cytochrome P450 (CYP3A4 and CYP3A5) and does not cause significant CYP3A4 inhibition or induction. It has a major active N-desmethylated metabolite AC-279, whose half-life is 200 h.


Company Information 

Article illustration





Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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