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Postion:Product Catalog >API>Specialty drugs>Dermatology drugs>Isotretinoin
Isotretinoin
  • Isotretinoin

Isotretinoin NEW

Price Get Latest Price
Package 1KG
Min. Order: 1KG
Supply Ability: 20 tons
Update Time: 2024-10-11

Product Details

Product Name: Isotretinoin CAS No.: 4759-48-2
Min. Order: 1KG Purity: 99%
Supply Ability: 20 tons Release date: 2024/10/11
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Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price



Isotretinoin Chemical Properties
Melting point 172-175 °C(lit.)
Boiling point 381.66°C (rough estimate)
density 1.0597 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. ?20°C
solubility Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
pka4.76±0.33(Predicted)
form Fine Crystalline Powder
color Yellow-orange to orange
Water Solubility insoluble
λmax354nm(EtOH)(lit.)
Merck 14,5228
Stability:Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKeySHGAZHPCJJPHSC-YCNIQYBTSA-N
CAS DataBase Reference4759-48-2(CAS DataBase Reference)
EPA Substance Registry SystemIsotretinoin (4759-48-2)



Use of  Isotretinoin

Isotretinoin Descrption

Isotretinoin (13-cis-Retinoic acid )is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. Clinically, 13-cis-Retinoic acid is primarily used in the treatment of severe recalcitrant nodular acne. Its effects include reducing the production of sebum, shrinking the size of the sebaceous glands, stabilizing keratinization, preventing comedones from forming, and reducing inflammation of inflammatory acne. Though the exact mechanism of action of 13-cis-Retinoic acid is not fully understood, studies have suggested that the compound alters DNA transcription and induces apoptosis in select types of cells throughout the body.


Function:

Both tretionirum and Vitamin A can stimulate skin growth and keep epidermic normal. Howerver, to spread on part of skin has no actual effect. Taking orally vitamin A is benefit to treat skin disorders. Applying vitamin A acid to skin partly could produce intensive pharmacological action. External use can slow down skin aging process for solarization, remove tiny wrinkles, and reduce skin roughness, so skin will become ruddy. 




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  • Since: 2021-12-10
  • Address: Qiaoxi District ,Shijiazhuang city, Hebei,Chicna
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