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Postion:Product Catalog >API>Antineoplastic agents>Antibiotics anticancer drugs>Doxorubicin hydrochloride
Doxorubicin hydrochloride
  • Doxorubicin hydrochloride

Doxorubicin hydrochloride

Price $95
Package 1g
Min. Order: 1g
Supply Ability: 100KG
Update Time: 2021-11-02

Product Details

Product Name: Doxorubicin hydrochloride CAS No.: 25316-40-9
Min. Order: 1g Purity: 99%
Supply Ability: 100KG Release date: 2021/11/02
Melting point 216 °C (dec.)(lit.)
alpha D20 +248±2° (c = 0.1 in methanol)
storage temp. 2-8°C
solubility H2O: 10 mg/mL, clear, red-orange
pkapKa 8.25±0.60 (Uncertain);8.43±0.70 (Uncertain);11.9±0.4 (Uncertain);12.95±0.1 (Uncertain);13.8±0.70 (Uncertain)
form solid
color orange to dark red
Water Solubility Soluble in water.
λmax497nm(H2O)(lit.)
Merck 14,3439
BRN 4229251
UsesUsed as an antineoplastic
UsesStrong fluorescent dye intercalating into DNA. Antitumour antibiotic. Effect of adriamycin on heart mitochondrial DNA. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent.
UsesAntibacterial;DNA intercalant
UsesDoxorubicin hydrochloride (adriamycin hydrochloride) is an antitumour agent that has been formulated as a salt to achieve higher water solubility. While the salt shares the same pharmacological properties as doxorubicin free base, its greater water solubility may offer advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems the free base and salt may behave differently.
UsesDoxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.[Cayman Chemical]


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  • Since: 2018-09-06
  • Address: Room B801, Financial Plaza, Jintai District, Baoji, Shaanxi, CN
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