(-)-α-Pinene NEW
| Price | $42 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: (-)-α-Pinene | CAS No.: 7785-26-4 |
| Purity: 98.60% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | (-)-α-Pinene |
| Description | (-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, acting as a partial modulator of GABAA-BZD receptors and directly binding to the BZD binding site of GABAA receptor. |
| In vitro | (1S)-(-)-Alpha-Pinene significantly increased the duration of non-rapid eye movement sleep (NREMS) and reduced the sleep latency by oral administration without affecting duration of rapid eye movement sleep and delta activity. (1S)-(-)-Alpha-Pinene potentiated the GABAA receptor-mediated synaptic response by increasing the decay time constant of sIPSCs in hippocampal CA1 pyramidal neurons[1]. These effects of (1S)-(-)-Alpha-Pinene on sleep and inhibitory synaptic response were mimicked by zolpidem, acting as a modulator for GABAA-BZD receptors, and fully antagonized by flumazenil, an antagonist for GABAA-BZD receptor. (1S)-(-)-Alpha-Pinene was found to bind to aromatic residues of α1- and -γ2 subunits of GABAA-BZD receptors in the molecular model[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (367.03 mM), Sonication is recommended. |
| Keywords | Gamma-aminobutyric acid Receptor | ()αPinene | Bacterial | Virus Protease | Endogenous Metabolite | γ-Aminobutyric acid Receptor | a-Pinene | α-Pinene | Alpha-Pinene | ( ) α Pinene | GABA Receptor | inhibit | Inhibitor |
| Inhibitors Related | Sucrose | Neomycin sulfate | Sulfamethoxazole sodium | Daidzein | Guanidine hydrochloride | Fumaric acid | Doxycycline | Ferulic Acid | Glycerol | Thymidine | Naringin | Dimethyl sulfoxide |
| Related Compound Libraries | Terpene Natural Product Library | Traditional Chinese Medicine Monomer Library | Anti-Viral Compound Library | Natural Product Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-virus Traditional Chinese Medicine Monomer Library | Ancient Chinese Classical Formulas Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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