γ-Linolenic Acid methyl ester NEW
Price | $29 |
Package | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: γ-Linolenic Acid methyl ester | CAS No.: 16326-32-2 |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | γ-Linolenic Acid methyl ester |
Description | γ-Linolenic Acid methyl ester (Methyl gamma-linolenate) is a weak leukotriene B4 (LTB4) receptor antagonist. |
In vitro | γ-Linolenic acid methyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets and dietary supplements. GLA was identified as an ω-6 fatty acid which could be elongated to arachidonic acid for endogenous eicosanoid synthesis. GLA was found to be a weak leukotriene B4 (LTB4) receptor antagonist, which was able to inhibit [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 μM |
In vivo | In an in-vivo model of LTB4-induced bronchoconstriction, γ-Linolenic acid methyl ester at a 1 mg/kg i.v. dose could result in 53% inhibition, indicating that essential fatty acids are LTB4 receptor antagonists, which may account in part for reported anti-inflammatory activities. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | dimethyl formamide : 100 mg/mL (341.88 mM) DMSO : 100 mg/mL (341.88 mM) |
Keywords | γ Linolenic Acid methyl ester | r-Linolenic Acid methyl ester | gamma-Linolenic Acid methyl ester | γLinolenic Acid methyl ester | γ-Linolenic Acid methyl ester |
Inhibitors Related | Moxilubant HCl | Montelukast sodium | LTB4-IN-1 | Linetastine | Croconazole | Montelukast | Darbufelone | Bestatin | FPL 55712 | Tebufelone | LTβR-IN-1 | Ticolubant |
Related Compound Libraries | Target-Focused Phenotypic Screening Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Inhibitor Library | NO PAINS Compound Library | Natural Product Library for HTS | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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