α-Humulene NEW
| Price | $74 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: α-Humulene | CAS No.: 6753-98-6 |
| Purity: 97.18% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | α-Humulene |
| Description | α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression. |
| In vitro | S. officinalis essential oil was obtained by hydrodistillation and fractionated with column chromatography; the essential oil and its fractions were analyzed by gas chromatography (GC) coupled to mass spectrometry (MS). The cytotoxic activity was evaluated in cellular lines of breast cancer MCF-7, colon cancer HCT-116, and murine macrophage RAW264.7 cell lines by the MTT assay Results: the sub-subfraction F1.1.1 of S. officinalis essential oil containing alpha-humulene present highest activity on RAW264.7 and HCT-116 with IC(50) values of 41.9 and 77.3 mu g/ml, respectively. The sub-subfraction F1.2.1 of S. officinalis essential oil with trans-caryophyllene(Alpha-caryophyllene) showed less activity on RAW246.7 and HCT-116 with IC(50) values of 90.5 and 145.8 mu g/ml. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ether : Soluble DMSO : 50 mg/mL (244.68 mM) Ethanol : Soluble |
| Keywords | α Humulene | Inhibitor | Humulene | a-caryophyllene | NOS | αHumulene | inhibit | COX | Nitric oxide synthases | α-Caryophyllene | Cyclooxygenase | α-caryophyllene | alpha-Humulene | α-Humulene | NO Synthase | a-Humulene |
| Inhibitors Related | Bismuth Subsalicylate | L-NAME hydrochloride | Ibuprofen | Acetaminophen | Diclofenac sodium | Glucosamine | Diclofenac Potassium | Apremilast | Paradol | Diallyl disulfide | Salicylic acid | Revaprazan hydrochloride |
| Related Compound Libraries | Terpene Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Miao medicine Compound Library | Tobacco Monomer Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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