(-)-Epigallocatechin Gallate NEW
| Price | $43 | $57 | $138 |
| Package | 50mg | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: (-)-Epigallocatechin Gallate | CAS No.: 989-51-5 |
| Purity: 99.43% | Supply Ability: 10g |
| Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名稱 | (-)-Epigallocatechin Gallate |
| 描述 | (-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells. |
| 細(xì)胞實(shí)驗(yàn) | LoVo, SW480, HCT-8, and HT-29 cells are seeded in 96-well plates at a concentration of 5×103?cells; each cell line is totally seeded in the 12 wells. Complete medium is added to the wells, up to 200 μL; the medium contains 0 μg/mL, 10 μg/mL, 20 μg/mL, and 35 μg/mL of epigallocatechol gallate. The inhibition rate=[1 - (absorbance of Epigallocatechol Gallate group - absorbance of control group)/(absorbance of control group - absorbance of blank control group)] × 100. |
| 體外活性 | METHODS: Human thyroid cancer cells TT, TPC-1 and ARO were treated with (-)-Epigallocatechin Gallate (10-200 μM) for 24 h. Cell viability was detected using MTS assay. |
| 體內(nèi)活性 | METHODS: To investigate the protective effect against acute injury, (-)-Epigallocatechin Gallate (200 mg/kg) was administered to ICR mice by gavage once a day for one week, followed by intraperitoneal injection of LPS (15 mg/kg) to induce acute injury. RESULTS: (-)-Epigallocatechin Gallate protects mice from LPS-induced acute stress, while stabilizing gut microorganisms, improving sphingolipid metabolism, and inhibiting harmful metabolite levels. [3] |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 100 mg/mL (218.16 mM) H2O : 50 mg/mL (109.08 mM), Sonication is recommended. Ethanol : 45.8 mg/mL (100 mM) |
| 關(guān)鍵字 | ( ) Epigallocatechin Gallate | Epigallocatechin Gallate | inhibit | FB-2 cells | Inhibitor | colorectal cancer | LPS-induced bone resorption | Endogenous Metabolite | cell proliferation. | Thyroid cancer | ()Epigallocatechin Gallate |
| 相關(guān)產(chǎn)品 | Sucrose | Emtricitabine | Glycerol | Thymidine |
| 相關(guān)庫 | 抗癌天然產(chǎn)物庫 | 風(fēng)味化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 天然產(chǎn)物庫 | 抗寄生蟲天然產(chǎn)物庫 | 抗衰老化合物庫 | 抗病毒中藥單體化合物庫 | 藥食同源庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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